Set2‐mediated H3K36 methylation states redundantly repress the production of antisense transcripts: role in transcription regulation
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DOI: 10.1002/2211-5463.13226
Abstract: Methyltransferase Set2‐mediated methylation of histone H3 lysine 36 (H3K36), which involves the addition of up to three methyl groups at this site, has been demonstrated to function in many chromatin‐coupled events. The methylation of H3K36… read more here.
Keywords: methylation; transcription; production antisense; antisense transcripts ... See more keywords
Set2 methyltransferase facilitates cell cycle progression by maintaining transcriptional fidelity
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DOI: 10.1093/nar/gkx1276
Abstract: Abstract Methylation of histone H3 lysine 36 (H3K36me) by yeast Set2 is critical for the maintenance of chromatin structure and transcriptional fidelity. However, we do not know the full range of Set2/H3K36me functions or the… read more here.
Keywords: transcriptional fidelity; cell cycle; cycle; cycle progression ... See more keywords
Evaluation of Sensitivity to Endocrine Therapy Index (SET2,3) for Response to Neoadjuvant Endocrine Therapy and Longer-Term Breast Cancer Patient Outcomes (Alliance Z1031)
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DOI: 10.1158/1078-0432.ccr-22-0068
Abstract: Abstract Purpose: To evaluate prediction of response and event-free survival (EFS) following neoadjuvant endocrine therapy by SET2,3 index of nonproliferation gene expression related to estrogen and progesterone receptors adjusted for baseline prognosis. Experimental Design: A… read more here.
Keywords: set2; therapy; rate; endocrine therapy ... See more keywords