Reversine exhibits antineoplastic activity in JAK2V617F-positive myeloproliferative neoplasms
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DOI: 10.1038/s41598-019-46163-2
Abstract: JAK2/STAT signaling participates in the Ph-negative myeloproliferative neoplasms (MPN) pathophysiology and has been targeted by ruxolitinib, a JAK1/2 inhibitor. In the present study, the impact of ruxolitinib treatment on cytoskeleton-related genes expression was explored. In… read more here.
Keywords: jak2v617f; set2 cells; reversine; expression ... See more keywords