Articles with "setd2 inactivated" as a keyword



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Abstract 2599: Targeting SETD2-inactivated cells with STF-62247 leads to cell cycle arrest

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-2599

Abstract: The SETD2 gene encodes a histone methyltransferase responsible for the trimethylation of histone 3 on lysine 36 (H3K36me3). While this canonic function plays a role in the regulation of cellular processes such as transcription, alternative… read more here.

Keywords: stf 62247; cell cycle; targeting setd2; setd2 inactivated ... See more keywords