Expansion and further delineation of the SETD5 phenotype leading to global developmental delay, variable dysmorphic features, and reduced penetrance
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DOI: 10.1111/cge.13132
Abstract: Diagnostic exome sequencing (DES) has aided delineation of the phenotypic spectrum of rare genetic etiologies of intellectual disability (ID). A SET domain containing 5 gene (SETD5) phenotype of ID and dysmorphic features has been previously… read more here.
Keywords: dysmorphic features; developmental delay; delineation; setd5 ... See more keywords
SET domain containing protein 5 (SETD5) enhances tumor cell invasion and is associated with a poor prognosis in non-small cell lung cancer patients
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DOI: 10.1186/s12885-019-5944-2
Abstract: BackgroundSET domain containing 5 (SETD5) is related to the aggressiveness of prostate and mammary cancers, but its association with non-small cell lung cancer (NSCLC) is unknown. Therefore, the purpose of this research was to determine… read more here.
Keywords: invasion; setd5; non small; cancer ... See more keywords
Downregulation of SETD5 Suppresses the Tumorigenicity of Hepatocellular Carcinoma Cells
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DOI: 10.14348/molcells.2022.0009
Abstract: Hepatocellular carcinoma (HCC) is an aggressive and incurable cancer. Although understanding of the molecular pathogenesis of HCC has greatly advanced, therapeutic options for the disease remain limited. In this study, we demonstrated that SETD5 expression… read more here.
Keywords: setd5; hepatocellular carcinoma; cells downregulation; hcc cells ... See more keywords