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SETD8C302R Mutation Revealed from Myofibroblastoma‐Discordant Monozygotic Twins Leads to p53/p21 Deficit and WEE1 Inhibitor Sensitivity

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Published in 2020 at "Advanced Science"

DOI: 10.1002/advs.202001041

Abstract: Abstract High‐throughput gene sequencing has identified various genetic variants as the culprits for some common hereditary cancers. However, the heritability of a substantial proportion of cancers remains unexplained, which may result from rare deleterious mutations… read more here.

Keywords: p53 p21; myofibroblastoma; wee1 inhibitor; setd8c302r mutation ... See more keywords