Articles with "setdb1 contributes" as a keyword



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Abstract A180: The histone methyltransferase SETDB1 contributes to melanoma tumorigenesis

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Published in 2018 at "Molecular Cancer Therapeutics"

DOI: 10.1158/1535-7163.targ-17-a180

Abstract: Histone modifications play a significant role in the development and progression of various cancers. The histone methyltransferase SETDB1 (SET domain, bifurcated 1) catalyzes the addition of methyl groups to histone H3 at lysine 9 (H3K9).… read more here.

Keywords: setdb1; histone methyltransferase; methyltransferase setdb1; contributes melanoma ... See more keywords