Setup and Use of HepaRG Cells in Cholestasis Research.
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DOI: 10.1007/978-1-4939-9420-5_19
Abstract: Since HepaRG cells can differentiate into well-polarized mature hepatocyte-like cells that synthesize, conjugate, and secrete bile acids, they represent an appropriate surrogate to primary human hepatocytes for investigations on drug-induced cholestasis mechanisms. In this chapter,… read more here.
Keywords: cells cholestasis; bile acids; setup use; heparg cells ... See more keywords