Neutral sphingomyelinase 2 controls exosome secretion by counteracting V-ATPase-mediated endosome acidification
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DOI: 10.1242/jcs.259324
Abstract: ABSTRACT During endosome maturation, neutral sphingomyelinase 2 (nSMase2, encoded by SMPD3) is involved in budding of intraluminal vesicles (ILVs) into late endosomes or multivesicular bodies (MVBs). Fusion of these with the plasma membrane results in… read more here.
Keywords: secretion; acidification; neutral sphingomyelinase; atpase ... See more keywords