Articles with "sevenless sos1" as a keyword



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Small molecule Son of Sevenless 1 (SOS1) inhibitors: a review of the patent literature.

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Published in 2021 at "Expert opinion on therapeutic patents"

DOI: 10.1080/13543776.2021.1952984

Abstract: IntroductionUp to 30% of all human cancers are driven by the overactivation of RAS signaling. Son of Sevenless 1 (SOS1) is a central node in RAS signaling pathways and modulation of SOS1-mediated RAS activation represents… read more here.

Keywords: son sevenless; small molecule; sos1; sevenless sos1 ... See more keywords