The predictive value of fibrinogen‐to‐albumin ratio in the active, severe active, and poor prognosis of systemic lupus erythematosus: A single‐center retrospective study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24621
Abstract: To evaluate the prediction and effect of fibrinogen‐to‐albumin ratio (FAR) on active, severe active, and poor prognosis of systemic lupus erythematosus (SLE). read more here.
Keywords: poor prognosis; severe active; fibrinogen albumin; albumin ratio ... See more keywords
Teprotumumab: a new avenue for the management of moderate-to-severe and active Graves’ orbitopathy?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-017-0717-8
Abstract: discrepancy [8],because of these conflicting results, the role of rituximab for moderate-to-severe and active GO remains to be defined in larger, multicenter RCTs [9]. The recent guidelines published by the European Thyroid Association/ European Group… read more here.
Keywords: graves orbitopathy; moderate severe; receptor; active graves ... See more keywords
Asymmetry indicates more severe and active disease in Graves’ orbitopathy: results from a prospective cross-sectional multicentre study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-020-01258-w
Abstract: Purpose Patients with Graves’ orbitopathy can present with asymmetric disease. The aim of this study was to identify clinical characteristics that distinguish asymmetric from unilateral and symmetric Graves’ orbitopathy. Methods This was a multi-centre study… read more here.
Keywords: disease; study; graves orbitopathy; severe active ... See more keywords
Efficacy and Safety of Ivarmacitinib in Patients with Moderate-to-Severe, Active, Ulcerative Colitis: A Phase II Study.
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DOI: 10.1053/j.gastro.2022.08.007
Abstract: BACKGROUND & AIMS Current therapies for ulcerative colitis (UC) fail to achieve satisfactory disease control. Selective inhibition of Janus kinase (JAK) type 1 may improve clinical outcomes in patients with UC while avoiding side effects… read more here.
Keywords: efficacy; moderate severe; severe active; week ... See more keywords
Semen Quality and Sperm DNA Integrity in Patients With Severe Active Inflammatory Bowel Disease and Effects of Tumour Necrosis Factor-alpha Inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjy198
Abstract: BACKGROUND AND AIMS The impact of severe inflammation on semen quality, including sperm DNA integrity, in men with inflammatory bowel disease [IBD] is unknown, as are the potential effects of anti-tumour necrosis factor-alpha [TNF-alpha] therapy.… read more here.
Keywords: tnf alpha; sperm dna; disease; anti tnf ... See more keywords
#748 Use of avacopan-based therapy among adults with severe active ANCA-associated vasculitis (AAV): a cross-sectional survey of physicians in Germany and the UK
Sign Up to like & getrecommendations! Published in 2025 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaf116.1285
Abstract: Avacopan, a selective C5aR1 inhibitor, has demonstrated efficacy and safety in its development program in patients with ANCA-associated vasculitis (AAV) (specifically granulomatosis with polyangiitis [GPA] and microscopic polyangiitis [MPA]) and has been approved in combination… read more here.
Keywords: therapy; survey; severe active; gpa mpa ... See more keywords