Outcomes of Severe Alcohol-Related Hepatitis with or without Early Liver Transplantation.
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.32219
Abstract: We read with great interest the article by Musto et al. in a recent issue of "Hepatology".(1) Evaluation of severe alcohol-related hepatitis (AH) demonstrated that 34 out of 144 patients (23.6%) recovered without liver transplantation… read more here.
Keywords: alcohol related; severe alcohol; liver transplantation; related hepatitis ... See more keywords
IL-1 receptor antagonist plus pentoxifylline and zinc for severe alcohol-associated hepatitis.
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DOI: 10.1002/hep.32478
Abstract: BACKGROUND & AIMS Patients with severe alcohol-associated hepatitis (AH) have high mortality. Corticosteroids improve survival only for 30 days. We targeted inflammation, cellular injury and gut leakiness in a randomized clinical trial comparing combination therapy… read more here.
Keywords: survival; alcohol associated; associated hepatitis; severe alcohol ... See more keywords
Clinical outcomes and gut microbiota analysis of severe alcohol-associated hepatitis patients undergoing healthy donor fecal transplant or pentoxifylline therapy: single-center experience from Kerala
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DOI: 10.1093/gastro/goac074
Abstract: Abstract Background Severe alcohol-associated hepatitis (SAH) patients with infections have a high short-term mortality rate. Gut microbiota dysbiosis plays an important role in the pathogenesis of SAH. Preliminary studies have demonstrated long-term benefits with healthy… read more here.
Keywords: gut microbiota; healthy donor; patients undergoing; analysis ... See more keywords
Alcohol Withdrawal Is an Oxidative Stress Challenge for the Brain: Does It Pave the Way toward Severe Alcohol-Related Cognitive Impairment?
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DOI: 10.3390/antiox11102078
Abstract: Alcohol use is a leading cause of mortality, brain morbidity, neurological complications and minor to major neurocognitive disorders. Alcohol-related neurocognitive disorders are consecutive to the direct effect of chronic and excessive alcohol use, but not… read more here.
Keywords: alcohol related; oxidative stress; brain; severe alcohol ... See more keywords