Alemtuzumab in relapsed immune severe aplastic anemia: Long‐term results of a phase II study
Sign Up to like & getrecommendations! Published in 2023 at "American Journal of Hematology"
DOI: 10.1002/ajh.26924
Abstract: Immune severe aplastic anemia (SAA) is characterized by pancytopenia and immune‐mediated bone marrow destruction. SAA may be treated with hematopoietic stem cell transplantation (HSCT) or immunosuppressive therapy (IST). However, 30% of patients treated with IST… read more here.
Keywords: long term; term results; severe aplastic; immune severe ... See more keywords
Outcome of anti-thymocyte immunoglobulin plus cyclosporine A for severe aplastic anaemia with chronic hepatitis B virus infection
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Hematology"
DOI: 10.1007/s00277-017-2918-9
Abstract: The influence of chronic hepatitis B virus (HBV) infection on the efficacy of intensive immunosuppressive treatment (IST) of severe aplastic anaemia (SAA) patients remains unclear. Previous reports on this topic have been mostly case reports… read more here.
Keywords: hbv; infection; hepatitis virus; chronic hepatitis ... See more keywords
A New Immunosuppressive Therapy for Very Severe Aplastic Anemia in Children with Autoantibodies
Sign Up to like & getrecommendations! Published in 2022 at "Current Medical Science"
DOI: 10.1007/s11596-022-2519-2
Abstract: At present, a number of very severe aplastic anemia (VSAA) patients cannot receive hematopoietic stem cell transplantation (HSCT) or standard immunosuppressive therapy (IST) due to the high cost of therapy, shortage of sibling donors, and… read more here.
Keywords: vsaa patients; csa hdp; therapy; immunosuppressive therapy ... See more keywords
Lessons from a patient with severe aplastic anemia complicated with COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "Asian Journal of Surgery"
DOI: 10.1016/j.asjsur.2020.07.007
Abstract: Abstract COVID-19 patients with preexisting diseases are at high risk of worse clinical outcomes. There is little data about patients with different comorbidities and how to deal with them. We reported a case of a… read more here.
Keywords: anemia complicated; aplastic anemia; complicated covid; patient severe ... See more keywords
Combined haploidentical and umbilical cord blood transplantation for severe aplastic anemia: Unique hematopoietic reconstitution.
Sign Up to like & getrecommendations! Published in 2018 at "Hematology/oncology and stem cell therapy"
DOI: 10.1016/j.hemonc.2018.08.002
Abstract: Hematopoietic stem cell transplant (HSCT) with matched sibling donor (MSD) is considered the first line of therapy for patients with severe aplastic anemia (SAA) who are read more here.
Keywords: cord; donor; blood; hematopoietic reconstitution ... See more keywords
Haploidentical Donor Bone Marrow Transplantation for Severe Aplastic Anemia.
Sign Up to like & getrecommendations! Published in 2018 at "Hematology/oncology clinics of North America"
DOI: 10.1016/j.hoc.2018.04.001
Abstract: Hematopoietic stem cell transplantation (bone marrow transplantation [BMT]) is the only curative treatment of severe aplastic anemia. BMT from an human leukocyte antigen (HLA)-matched sibling donor is the standard of care for young patients; immunosuppressive… read more here.
Keywords: marrow transplantation; aplastic anemia; severe aplastic; bone marrow ... See more keywords
Late chimerical status after bone marrow transplantation in severe aplastic anemia according to two different preparatory regimens
Sign Up to like & getrecommendations! Published in 2018 at "Hematology, Transfusion and Cell Therapy"
DOI: 10.1016/j.htct.2017.11.011
Abstract: Background This study investigated the influence of two conditioning regimens on the chimerical status of 104 patients with acquired severe aplastic anemia. Methods Patients were monitored for at least 18 months after related bone marrow… read more here.
Keywords: recovery; chimerical status; chimerism; group ... See more keywords
Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis
Sign Up to like & getrecommendations! Published in 2019 at "Medical Mycology Case Reports"
DOI: 10.1016/j.mmcr.2019.01.001
Abstract: Severe aplastic anemia (SAA) is a hematological disease resulting in pancytopenia due to bone marrow failure. Treatment consists of immunosppressive therapy, or allo-SCT. Patients with aplastic anemia are predisposed to invasive fungal infections due to… read more here.
Keywords: disseminated mucormycosis; treatment; aplastic anemia; severe aplastic ... See more keywords
Haploidentical transplantation for pediatric patients with acquired severe aplastic anemia
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DOI: 10.1038/bmt.2016.281
Abstract: Techniques for haploidentical hematopoietic stem cell transplantation (haplo-HSCT) to treat severe aplastic anemia (SAA) have recently improved, but no protocol has been evaluated in a large number of pediatric patients. Fifty-two children with SAA received… read more here.
Keywords: aplastic anemia; haplo hsct; transplantation; pediatric patients ... See more keywords
Immunosuppressive therapy versus haploidentical transplantation in adults with acquired severe aplastic anemia
Sign Up to like & getrecommendations! Published in 2019 at "Bone Marrow Transplantation"
DOI: 10.1038/s41409-018-0410-3
Abstract: Our study aimed to compare treatment outcomes between hematopoietic stem cell transplantation (HSCT) from haploidentical donors (HID) and immunosuppressive therapy (IST) in adults with acquired severe aplastic anemia (SAA). The medical records of 113 SAA… read more here.
Keywords: immunosuppressive therapy; acquired severe; group; transplantation ... See more keywords
Acute hepatitis as a prequel to very severe aplastic anemia.
Sign Up to like & getrecommendations! Published in 2018 at "Zeitschrift fur Gastroenterologie"
DOI: 10.1055/s-0043-121737
Abstract: Severe aplastic anemia is a rare and potentially life-threatening disease of the bone marrow often requiring allogeneic hematopoietic stem cell transplantation. Pathogenesis of the disease can vary and often remains enigmatic. Occasionally, severe aplastic anemia… read more here.
Keywords: hepatitis; acute hepatitis; aplastic anemia; severe aplastic ... See more keywords