Safety of biologics in severe asthmatic patients with SARS‐CoV‐2 infection: A prospective study
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DOI: 10.1002/ppul.26298
Abstract: Asthma guidelines have recommended continuing treatment with biologics during coronavirus disease 2019 (COVID‐19) pandemic. However, a continuation of treatment with biologics in patients with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has been little investigated. read more here.
Keywords: asthmatic patients; safety biologics; severe asthmatic; patients sars ... See more keywords
Is immunotherapy safe for treatment of severe asthma
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DOI: 10.1097/aci.0000000000000853
Abstract: Purpose of review The benefits of allergen immunotherapy (AIT), including subcutaneous allergen immunotherapy (SCIT) and sublingual allergen immunotherapy (SLIT), for IgE-mediated asthma are well established, especially for dust mite. This review will explore whether the… read more here.
Keywords: asthmatic patients; asthma; severe asthmatic; treatment ... See more keywords
Neutrophil Extracellular Traps Are Found in Bronchoalveolar Lavage Fluids of Horses With Severe Asthma and Correlate With Asthma Severity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.921077
Abstract: Asthma encompasses a spectrum of heterogenous immune-mediated respiratory disorders sharing a similar clinical pattern characterized by cough, wheeze and exercise intolerance. In horses, equine asthma can be subdivided into severe or moderate asthma according to… read more here.
Keywords: asthma; neutrophil extracellular; equine asthma; severity ... See more keywords
Bcl10 Regulates Lipopolysaccharide-Induced Pro-Fibrotic Signaling in Bronchial Fibroblasts from Severe Asthma Patients
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DOI: 10.3390/biomedicines10071716
Abstract: Subepithelial fibrosis is a characteristic hallmark of airway remodeling in asthma. Current asthma medications have limited efficacy in treating fibrosis, particularly in patients with severe asthma, necessitating a deeper understanding of the fibrotic mechanisms. The… read more here.
Keywords: bronchial fibroblasts; fibrotic signaling; fibrosis; pro fibrotic ... See more keywords
Severe Asthmatic Responses: The Impact of TSLP
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DOI: 10.3390/ijms24087581
Abstract: Asthma is a chronic inflammatory disease that affects the lower respiratory system and includes several categories of patients with varying features or phenotypes. Patients with severe asthma (SA) represent a group of asthmatics that are… read more here.
Keywords: disease; tslp; responses impact; impact tslp ... See more keywords
Mepolizumab Improves Outcomes of Chronic Rhinosinusitis with Nasal Polyps in Severe Asthmatic Patients: A Multicentric Real-Life Study
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DOI: 10.3390/jpm12081304
Abstract: Objective: The upcoming introduction of mepolizumab represents a promising treatment for chronic rhinosinusitis with nasal polyps (CRSwNP). The present study aimed to evaluate the effectiveness of mepolizumab on sinonasal outcomes of comorbid CRSwNP and severe… read more here.
Keywords: asthmatic patients; mepolizumab; score; treatment ... See more keywords