Articles with "severe autoimmune" as a keyword



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TLR8/TLR7 dysregulation due to a novel TLR8 mutation causes severe autoimmune hemolytic anemia and autoinflammation in identical twins

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Published in 2022 at "American Journal of Hematology"

DOI: 10.1002/ajh.26452

Abstract: Our study presents a novel germline c.1715G>T (p.G572V) mutation in the gene encoding Tollā€like receptor 8 (TLR8) causing an autoimmune and autoinflammatory disorder in a family with monozygotic male twins, who suffer from severe autoimmune… read more here.

Keywords: tlr8; severe autoimmune; autoimmune hemolytic; mutation causes ... See more keywords
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Severe Autoimmune intravascular hemolytic anemia in patients receiving Alemtuzumab for Multiple sclerosis.

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Published in 2022 at "Blood advances"

DOI: 10.1182/bloodadvances.2022008968

Abstract: Alemtuzumab is a recombinant humanized anti-CD52 monoclonal antibody against a glycosylated, glycosylphosphatidylinositol-anchored, cell-surface protein (CD52) which is expressed at high levels on T and B lymphocytes. 1,2 It was approved by the European Medicines Agency… read more here.

Keywords: autoimmune intravascular; sclerosis; severe autoimmune; multiple sclerosis ... See more keywords
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Clinical Features, Treatment, and Prognostic Factors in Neuronal Surface Antibody-Mediated Severe Autoimmune Encephalitis

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.890656

Abstract: Objective This study aimed to determine the clinical characteristics and evaluate the efficacy of immunotherapy and the long-term prognosis of severe autoimmune encephalitis (AE) in China. Methods Clinical features, laboratory or radiological findings, and treatment… read more here.

Keywords: severe autoimmune; treatment; autoimmune encephalitis; clinical features ... See more keywords