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Published in 2025 at "Gastroenterology"
DOI: 10.1053/j.gastro.2025.01.129
Abstract: Upadacinitib (UPA), a narrow spectrum Janus kinase inhibitor, is an FDA-approved therapy for adults with inflammatory bowel disease (IBD). It is not currently approved for pediatric IBD and instead must be used as an off-label…
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Keywords:
severe colitis;
therapy;
response;
acute severe ... See more keywords
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Published in 2022 at "Clinics in colon and rectal surgery"
DOI: 10.1055/s-0041-1740030
Abstract: The management of hospitalized patients with acute, severe ulcerative colitis involves close coordination among a multidisciplinary team. For patients not improving on intravenous corticosteroids, surgical consultation should be sought. The remaining hospital course requires frequent…
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Keywords:
severe colitis;
colitis need;
gastroenterologists surgeons;
management ... See more keywords
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Published in 2017 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjw159
Abstract: Background and Aims Acute severe colitis [ASC] is associated with major morbidity. We aimed to develop and externally validate an index that predicted ASC within 3 years of diagnosis. Methods The development cohort included patients…
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Keywords:
severe colitis;
risk;
diagnosis;
acute severe ... See more keywords
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Published in 2020 at "Pediatric and Developmental Pathology"
DOI: 10.1177/1093526620929477
Abstract: Background Multiple prior studies have looked at clinical and laboratory parameters in ulcerative colitis to predict prognosis, but individual histologic features of inflammation and their prognostic significance have not been well studied. The purpose of…
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Keywords:
severe colitis;
histologic features;
acute severe;
pathology ... See more keywords
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Published in 2024 at "Internal Medicine"
DOI: 10.2169/internalmedicine.4224-24
Abstract: A 74-year-old woman developed acute severe colitis after receiving her sixth mRNA vaccine against coronavirus disease 2019 (COVID-19). On the day after vaccination, she experienced bloody diarrhea, abdominal pain, and high-grade fever. Laboratory tests revealed…
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Keywords:
severe colitis;
coronavirus disease;
acute severe;
vaccination ... See more keywords