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Published in 2017 at "Archivos De Bronconeumologia"
DOI: 10.1016/j.arbr.2017.01.005
Abstract: Exercise intolerance is a hallmark of severe chronic obstructive pulmonary disease (COPD), resulting from early onset of breathlessness and fatigue on exertion, due in turn to impaired oxygen uptake, reduced cardiovascular fitness and skeletal muscle…
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Keywords:
severe copd;
stimulation;
training;
exercise ... See more keywords
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Published in 2021 at "Chest"
DOI: 10.1016/j.chest.2021.02.012
Abstract: BACKGROUND Pulmonary hypertension in chronic obstructive pulmonary disease (PH-COPD) is a poorly investigated clinical condition. RESEARCH QUESTION Which factors determine outcome of PH-COPD? STUDY DESIGN AND METHODS We analyzed the characteristics and outcome of patients…
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Keywords:
chronic obstructive;
pulmonary hypertension;
severe copd;
disease ... See more keywords
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Published in 2022 at "Clinical nutrition"
DOI: 10.1016/j.clnu.2022.01.015
Abstract: BACKGROUND & AIM Patients with early-onset severe COPD are often female and characterized by severe emphysema. Extrapulmonary disease manifestations have not yet been investigated in this clinical phenotype. Therefore, this study aimed to study the…
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Keywords:
health;
onset severe;
copd;
patients early ... See more keywords
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Published in 2017 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2017.08.020
Abstract: BACKGROUND The use of long-acting bronchodilators is an essential component of the management of chronic obstructive pulmonary disease (COPD). The GOLDEN 5 Phase III, randomized, active-controlled, open-label study was conducted to evaluate the long-term safety…
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Keywords:
severe copd;
glycopyrrolate;
study;
copd ... See more keywords
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Published in 2019 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2019.08.010
Abstract: BACKGROUND Single inhaler triple therapies providing an inhaled corticosteroid, a long-acting muscarinic antagonist, and a long-acting β2-agonist (ICS/LAMA/LABAs) are an emerging treatment option for chronic obstructive pulmonary disease (COPD). Nevertheless, questions remain regarding the optimal…
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Keywords:
moderate severe;
study;
formoterol fumarate;
severe copd ... See more keywords
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Published in 2022 at "Expert Review of Respiratory Medicine"
DOI: 10.1080/17476348.2022.2145951
Abstract: ABSTRACT Introduction Evidence from non-randomized studies shows benefits for single-inhaler users compared with multiple-inhaler users who receive the same medication. As a result, comparative cost-effectiveness studies are required to inform treatment decisions with an increasing…
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Keywords:
inhaler;
cost;
patients severe;
severe copd ... See more keywords
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Published in 2023 at "Emergency Medicine International"
DOI: 10.1155/2023/5945191
Abstract: Background This study aimed to investigate the predictive value of general clinical data, blood test indexes, and ventilation function test indexes on the severity of chronic obstructive pulmonary disease (COPD). Methods A total of 141…
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Keywords:
copd;
logistic regression;
count;
severity ... See more keywords
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Published in 2021 at "Respiration"
DOI: 10.1159/000517781
Abstract: Background: Long-term azithromycin therapy significantly reduces the frequency of COPD exacerbations (ECOPD). However, previous studies have used different dosing regimens, and the efficacy of these regimens has not been compared. Objective: Compare the efficacy of…
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Keywords:
low dose;
high dose;
severe copd;
group ... See more keywords
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Published in 2023 at "Therapeutic Advances in Respiratory Disease"
DOI: 10.1177/17534666231162250
Abstract: Objective: Pulmonary rehabilitation (PR) has been considered to be an effective treatment method for various respiratory diseases. However, the effects of exercise-based PR on patients with severe/very severe chronic obstructive pulmonary disease (COPD) are unclear.…
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Keywords:
effects exercise;
quality;
severe copd;
severe severe ... See more keywords
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Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/1393003.congress-2017.pa2575
Abstract: Patients with COPD show impairments in several autonomic function (AF) parameters such as heart rate variability (HRV) and baroreceptor reflex sensitivity (BRS). This study assessed AF using a standardized battery of test among subjects with…
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Keywords:
autonomic function;
severe copd;
function subjects;
subjects copd ... See more keywords
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Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2018.pa2001
Abstract: Background: Economic evaluation of non-pharmacological interventions in severe COPD patients is scarce. The COPD patient Management European Trial (COMET) compared a Disease Management (DM) intervention versus Usual Management (UM) in 4 countries: France, Italy, Germany…
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Keywords:
intervention;
severe copd;
management;
comet ... See more keywords