Circulating B10 regulatory cells are decreased in severe and critical COVID‐19
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.5covcra0721-387rr
Abstract: The contribution of B cells in COVID‐19 pathogenesis, beyond the production of specific antibodies against SARS‐CoV‐2, is still not well understood. Since one of their most relevant functional roles includes their immune‐suppressive mechanisms, we decided… read more here.
Keywords: regulatory cells; critical covid; severe critical; circulating b10 ... See more keywords
Comparison of demographic and clinical characteristics of hospitalized COVID-19 patients with severe/critical illness in the first wave vs the second wave.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medical virology"
DOI: 10.1002/jmv.27319
Abstract: BACKGROUND Due to current advances and growing experience in the management of coronavirus Disease 2019 (COVID-19), the outcome of COVID-19 patients with severe/critical illness would be expected to be better in the second wave compared… read more here.
Keywords: covid patients; critical illness; severe critical; wave ... See more keywords
The skin as a critical window in unveiling the pathophysiologic principles of COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Clinics in Dermatology"
DOI: 10.1016/j.clindermatol.2021.07.001
Abstract: The severe acute respiratory distress syndrome-associated coronavirus-2 (SARS-CoV-2), the etiologic agent of Coronavirus disease 2019 (COVID-19), is a single-stranded RNA virus whose sequence is known. COVID-19 is associated with a heterogeneous clinical phenotype ranging from… read more here.
Keywords: severe critical; covid; pathophysiologic principles; spike glycoprotein ... See more keywords
CT features of COVID-19 patients with two consecutive negative RT-PCR tests after treatment
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68509-x
Abstract: The objective of this study is to expound the CT features of COVID-19 patients whose throat swab samples were negative for two consecutive nucleic acid tests after treatment. We retrospectively reviewed 46 COVID-19 patients with… read more here.
Keywords: covid patients; two consecutive; severe critical; consecutive negative ... See more keywords
Analysis of related factors of plasma antibody levels in patients with severe and critical COVID-19
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-52572-9
Abstract: Coronavirus disease 2019 (COVID-19) continues to impact global public health. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become less virulent as it mutates, prompting China to ease restrictions at the end of 2022.… read more here.
Keywords: antibody levels; covid; antibody; plasma antibody ... See more keywords
Efficacy of additional hemoperfusion in hospitalized patients with severe to critical COVID-19 disease
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-68592-4
Abstract: The evidence supporting additional hemoperfusion (HP) with cytokine adsorbents for improving clinical outcomes in severe to critical coronavirus disease 2019 (COVID-19) patients remains limited. We compared severe to critical COVID-19 patients who received additional HP… read more here.
Keywords: critical covid; disease; covid; severe critical ... See more keywords
Diagnostic Value of Natural Killer Cells, CD56+ CD16+ Natural Killer Cells, NLRP3, and Lactate Dehydrogenase in Severe/Critical COVID-19: A Prospective Longitudinal Study According to the Severe/Critical COVID-19 Definitions.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2022.0060
Abstract: Innate immunity, as the first line of defense of our immune system, plays a crucial role in defending against SARS-CoV-2 infection and also its immunopathogenesis. We aim to investigate the immune status of natural killer… read more here.
Keywords: critical covid; natural killer; killer cells; covid ... See more keywords
P-1901. Statin Use and Severe/Critical/Fatal Outcomes in Individuals with COVID-19
Sign Up to like & getrecommendations! Published in 2025 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofae631.2062
Abstract: Abstract Background There are conflicting results regarding the effects of statins upon outcomes in individuals with COVID-19. Several studies demonstrated a beneficial effect on survival, with others failing to demonstrate a beneficial effect, or even… read more here.
Keywords: statin recipients; outcomes individuals; severe critical; individuals covid ... See more keywords
Timing of tofacitinib therapy is critical to improving outcomes in severe-critical COVID-19 infection: A retrospective study from a tertiary care hospital
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000030975
Abstract: Describe the use of tofacitinib in severe and critical coronavirus disease-2019 (COVID-19), and explore the association of drug initiation time with survival. A retrospective study of inpatients with severe or critical COVID-19 at a tertiary… read more here.
Keywords: retrospective study; severe critical; tofacitinib; covid ... See more keywords
Epidemiological investigation of the first 5685 cases of SARS-CoV-2 infection in Qatar, 28 February–18 April 2020
Sign Up to like & getrecommendations! Published in 2020 at "BMJ Open"
DOI: 10.1136/bmjopen-2020-040428
Abstract: Objective To define the epidemiological curve of COVID-19 in Qatar and determine factors associated with severe or critical illness. Design Case series of first 5685 COVID-19 cases in Qatar. Setting and participants All confirmed COVID-19… read more here.
Keywords: critical illness; severe critical; february april; qatar ... See more keywords
Diminution of STING Expression in the Blood of Patients with Severe or Critical COVID-19 Pneumonia
Sign Up to like & getrecommendations! Published in 2022 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000526661
Abstract: Introduction: Cytokine storm and critical COVID-19 pneumonia are caused in at least 10% of patients by inborn errors of or auto-Abs to type I IFNs. The pathogenesis of life-threatening COVID-19 pneumonia in other patients remains… read more here.
Keywords: sting expression; covid pneumonia; patients severe; expression ... See more keywords