Circulating B10 regulatory cells are decreased in severe and critical COVID‐19
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.5covcra0721-387rr
Abstract: The contribution of B cells in COVID‐19 pathogenesis, beyond the production of specific antibodies against SARS‐CoV‐2, is still not well understood. Since one of their most relevant functional roles includes their immune‐suppressive mechanisms, we decided… read more here.
Keywords: regulatory cells; critical covid; severe critical; circulating b10 ... See more keywords
Comparison of demographic and clinical characteristics of hospitalized COVID-19 patients with severe/critical illness in the first wave vs the second wave.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medical virology"
DOI: 10.1002/jmv.27319
Abstract: BACKGROUND Due to current advances and growing experience in the management of coronavirus Disease 2019 (COVID-19), the outcome of COVID-19 patients with severe/critical illness would be expected to be better in the second wave compared… read more here.
Keywords: covid patients; critical illness; severe critical; wave ... See more keywords
The skin as a critical window in unveiling the pathophysiologic principles of COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Clinics in Dermatology"
DOI: 10.1016/j.clindermatol.2021.07.001
Abstract: The severe acute respiratory distress syndrome-associated coronavirus-2 (SARS-CoV-2), the etiologic agent of Coronavirus disease 2019 (COVID-19), is a single-stranded RNA virus whose sequence is known. COVID-19 is associated with a heterogeneous clinical phenotype ranging from… read more here.
Keywords: severe critical; covid; pathophysiologic principles; spike glycoprotein ... See more keywords
CT features of COVID-19 patients with two consecutive negative RT-PCR tests after treatment
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68509-x
Abstract: The objective of this study is to expound the CT features of COVID-19 patients whose throat swab samples were negative for two consecutive nucleic acid tests after treatment. We retrospectively reviewed 46 COVID-19 patients with… read more here.
Keywords: covid patients; two consecutive; severe critical; consecutive negative ... See more keywords
Diagnostic Value of Natural Killer Cells, CD56+ CD16+ Natural Killer Cells, NLRP3, and Lactate Dehydrogenase in Severe/Critical COVID-19: A Prospective Longitudinal Study According to the Severe/Critical COVID-19 Definitions.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2022.0060
Abstract: Innate immunity, as the first line of defense of our immune system, plays a crucial role in defending against SARS-CoV-2 infection and also its immunopathogenesis. We aim to investigate the immune status of natural killer… read more here.
Keywords: critical covid; natural killer; killer cells; covid ... See more keywords
Timing of tofacitinib therapy is critical to improving outcomes in severe-critical COVID-19 infection: A retrospective study from a tertiary care hospital
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000030975
Abstract: Describe the use of tofacitinib in severe and critical coronavirus disease-2019 (COVID-19), and explore the association of drug initiation time with survival. A retrospective study of inpatients with severe or critical COVID-19 at a tertiary… read more here.
Keywords: retrospective study; severe critical; tofacitinib; covid ... See more keywords
Epidemiological investigation of the first 5685 cases of SARS-CoV-2 infection in Qatar, 28 February–18 April 2020
Sign Up to like & getrecommendations! Published in 2020 at "BMJ Open"
DOI: 10.1136/bmjopen-2020-040428
Abstract: Objective To define the epidemiological curve of COVID-19 in Qatar and determine factors associated with severe or critical illness. Design Case series of first 5685 COVID-19 cases in Qatar. Setting and participants All confirmed COVID-19… read more here.
Keywords: critical illness; severe critical; february april; qatar ... See more keywords
Diminution of STING Expression in the Blood of Patients with Severe or Critical COVID-19 Pneumonia
Sign Up to like & getrecommendations! Published in 2022 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000526661
Abstract: Introduction: Cytokine storm and critical COVID-19 pneumonia are caused in at least 10% of patients by inborn errors of or auto-Abs to type I IFNs. The pathogenesis of life-threatening COVID-19 pneumonia in other patients remains… read more here.
Keywords: sting expression; covid pneumonia; patients severe; expression ... See more keywords
Clinical Features of COVID-19 Patients With Venous Thromboembolism
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DOI: 10.1177/10760296211013104
Abstract: This study aimed to assess the clinical features of coronavirus disease 2019 (COVID-19) patients with VTE, to help develop preventive measures for venous thromboembolism (VTE in COVID-19) cases. COVID-19 patients admitted to Henan Provincial People’s… read more here.
Keywords: covid patients; covid cases; clinical features; severe critical ... See more keywords
Retrospective analysis of influencing factors on the efficacy of mechanical ventilation in severe and critical COVID-19 patients.
Sign Up to like & getrecommendations! Published in 2021 at "World journal of clinical cases"
DOI: 10.12998/wjcc.v9.i31.9481
Abstract: BACKGROUND The novel coronavirus disease 2019 (COVID-19) has spread widely around the world with strong infectivity, rapid mutation and a high mortality rate. Mechanical ventilation has been included in the Diagnosis and Treatment Protocol for… read more here.
Keywords: severe critical; critical covid; covid; covid patients ... See more keywords
Clinical laboratory parameters associated with severe or critical novel coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis
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DOI: 10.1371/journal.pone.0239802
Abstract: Background To date, several clinical laboratory parameters associated with Coronavirus disease 2019 (COVID-19) severity have been reported. However, these parameters have not been observed consistently across studies. The aim of this review was to assess… read more here.
Keywords: severe critical; disease; covid; laboratory parameters ... See more keywords