Articles with "severe crswnp" as a keyword



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AROMA: real-world global registry of dupilumab for chronic rhinosinusitis with nasal polyps

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Published in 2022 at "ERJ Open Research"

DOI: 10.1183/23120541.00085-2022

Abstract: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a predominantly type 2 inflammatory disease of the nasal and paranasal sinuses. Dupilumab is a monoclonal antibody that blocks the shared receptor component for interleukin-4 and interleukin-13, which… read more here.

Keywords: global registry; severe crswnp; registry; dupilumab ... See more keywords
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Rapid and Continuing Improvements in Nasal Symptoms with Dupilumab in Patients with Severe CRSwNP

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Published in 2022 at "Journal of Asthma and Allergy"

DOI: 10.2147/jaa.s355391

Abstract: Purpose In the phase 3 SINUS-24 (NCT02912468) and SINUS-52 (NCT02898454) studies in adults with severe chronic rhinosinusitis with nasal polyps (CRSwNP), dupilumab significantly improved the co-primary endpoints of change from baseline to Week 24 in… read more here.

Keywords: rapid continuing; severe crswnp; patients severe; dupilumab treated ... See more keywords