S31 Dupilumab reduces severe exacerbations across baseline disease characteristics in patients with elevated baseline type 2 biomarkers: the LIBERTY ASTHMA QUEST study
Sign Up to like & getrecommendations! Published in 2019 at "Thorax"
DOI: 10.1136/thorax-2019-btsabstracts2019.37
Abstract: Introduction Dupilumab, a fully human VelocImmune®-derived monoclonal antibody, blocks the shared receptor component for interleukin (IL)-4/IL-13, key drivers of type 2 inflammation in multiple diseases. In the phase 3 LIBERTY ASTHMA QUEST study (NCT02414854), add-on… read more here.
Keywords: severe asthma; baseline disease; characteristics patients; disease characteristics ... See more keywords
The five-repetition sit-to-stand test is a predictive factor of severe exacerbations in COPD
Sign Up to like & getrecommendations! Published in 2021 at "Therapeutic Advances in Chronic Disease"
DOI: 10.1177/2040622320986718
Abstract: Background: Although the six-minute-walk test (6MWT) has been used to predict chronic obstructive pulmonary disease (COPD) exacerbations, additional research is necessary to identify more rapid, simpler tests that are directly associated with exacerbations, such as… read more here.
Keywords: sit stand; severe exacerbations; repetition sit; 5sts test ... See more keywords
Impact of moderate and severe exacerbations in severe COPD patients
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DOI: 10.1183/13993003.congress-2018.pa3865
Abstract: Background: Acute exacerbations have a significant and permanent impact on lung function and quality of life (QoL) in patients with COPD. Previous studies focused on lung function in COPD; studies exploring the impact of exacerbations… read more here.
Keywords: severe exacerbations; copd patients; severe copd; impact ... See more keywords