The neurosurgical management of Severe Hemophilia A and Moyamoya (SHAM): challenges, strategies, and literature review
Sign Up to like & getrecommendations! Published in 2022 at "Child's Nervous System"
DOI: 10.1007/s00381-022-05489-5
Abstract: Severe Hemophilia A and Moyamoya arteriopathy (SHAM syndrome) is a rare genetic disorder caused by deletion of portions of the cytogenic band Xq28. A case of SHAM syndrome requiring bilateral cerebral revascularization is described with… read more here.
Keywords: hemophilia moyamoya; sham syndrome; severe hemophilia; hemophilia ... See more keywords
First application of focused low-energy extracorporeal shockwave therapy in a patient with severe hemophilia A and plantar fasciitis
Sign Up to like & getrecommendations! Published in 2020 at "Wiener klinische Wochenschrift"
DOI: 10.1007/s00508-020-01687-w
Abstract: Hemophilia A is a rare X-chromosome linked congenital bleeding disorder caused by a deficiency of coagulation factor VIII. People with severe hemophilia have clotting factor levels read more here.
Keywords: severe hemophilia; plantar fasciitis; extracorporeal; therapy ... See more keywords
Successful endoscopic sphincterotomy for choledocholithiasis in a patient with severe hemophilia A and inhibitors
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Journal of Gastroenterology"
DOI: 10.1007/s12328-018-0826-8
Abstract: Endoscopic sphincterotomy (ES) is a standard procedure for bile duct stone removal. However, the safety of ES in patients with hemophilia remains unknown. We treated a 46-year-old man who had choledocholithiasis and severe hemophilia A… read more here.
Keywords: severe hemophilia; choledocholithiasis; factor; endoscopic sphincterotomy ... See more keywords
Joint status and related risk factors in patients with severe hemophilia A: a single-center cross-sectional study.
Sign Up to like & getrecommendations! Published in 2022 at "Hematology"
DOI: 10.1080/16078454.2021.2019892
Abstract: OBJECTIVES Hemophilic arthropathy is the most common complication of severe hemophilia A. This study aims to investigated joint status and related risk factors in patients with severe hemophilia A (PWSHA). METHODS This single-center study included… read more here.
Keywords: study; hjhs scores; treatment; severe hemophilia ... See more keywords
Phase 1, single‐dose escalating study of marzeptacog alfa (activated), a recombinant factor VIIa variant, in patients with severe hemophilia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.14247
Abstract: Essentials Marzeptacog alfa (activated) [MarzAA] is a novel variant of activated human factor VII. A phase 1 dose escalation trial of MarzAA was conducted in subjects with severe hemophilia. MarzAA was safe and tolerated at… read more here.
Keywords: marzeptacog alfa; severe hemophilia; phase; alfa activated ... See more keywords
Neutralizing antidrug antibody to emicizumab in a patient with severe hemophilia A with inhibitors: New case with detailed laboratory evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.14957
Abstract: Hemophilia A is an inherited bleeding disorder characterized by deficiency of the coagulation protein factor VIII. Development of clotting factor concentrates has resulted in an excellent prognosis for this historically fatal disease. However, neutralizing antidrug… read more here.
Keywords: severe hemophilia; neutralizing antidrug; antibody; patient severe ... See more keywords
Homeopathic Medicine Reduces Pain and Hemarthrosis in Moderate and Severe Hemophilia: A Multicentric Study
Sign Up to like & getrecommendations! Published in 2018 at "Complementary Medicine Research"
DOI: 10.1159/000486557
Abstract: Background: Hemarthrosis is a common clinical presentation of patients with severe and moderately severe hemophilia. Severe pain, swelling, and loss of function involving knee, ankle, elbow, and shoulder joints are commonly seen. In India, except… read more here.
Keywords: medicine; severe hemophilia; hemarthrosis; homeopathic medicines ... See more keywords
Masculinity Challenges for Men With Severe Hemophilia
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Men's Health"
DOI: 10.1177/1557988319872626
Abstract: Hemophilia is a congenital bleeding disorder that mainly affects men. Men with severe hemophilia experience stigma because they are unable to live up to various ideals of masculinity. This study involves a qualitative analysis of… read more here.
Keywords: men severe; severe hemophilia; masculinity challenges; disorder ... See more keywords
FVIII Immunogenicity—Bioinformatic Approaches to Evaluate Inhibitor Risk in Non-severe Hemophilia A
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01498
Abstract: The life-long inhibitor risk in non-severe hemophilia A has been an important clinical and research focus in recent years. Non-severe hemophilia A is most commonly caused by point mutation, missense F8 genotypes, of which over… read more here.
Keywords: risk; inhibitor; severe hemophilia; non severe ... See more keywords
A single-center study of bone mineral density in adult patients with severe hemophilia A in correlation with markers of bone metabolism.
Sign Up to like & getrecommendations! Published in 2023 at "Folia medica"
DOI: 10.3897/folmed.65.e75414
Abstract: INTRODUCTION Osteopenia and osteoporosis are well-known hemophilia A comorbidities. The pathogenesis of bone turnover alteration resulting in reduced bone mass includes impaired osteoblastic differentiation and disinhibition of RANKL-induced osteoclastogenesis as a result of a low… read more here.
Keywords: mineral density; bmd; adult patients; severe hemophilia ... See more keywords
Assessment of healthcare measures, healthcare resource use, and cost of care among severe hemophilia A patients in Mumbai region of India
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Postgraduate Medicine"
DOI: 10.4103/jpgm.jpgm_701_16
Abstract: Background: In India, the low public health priority given to rare disorders such as hemophilia hinders their management and optimal care, leading to relatively poor health outcomes. This study aims to profile the multidimensional health… read more here.
Keywords: severe hemophilia; use; mumbai region; health ... See more keywords