Preliminary experience with tigecycline treatment for severe infection in children
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pediatrics"
DOI: 10.1007/s00431-018-3208-9
Abstract: Severe infection is a primary cause of mortality in children facing challenges from multidrug-resistant (MDR) pathogens, particularly MDR Acinetobacter baumannii. Tigecycline has an expanded spectrum of antibacterial activity, and some successful instances of its use… read more here.
Keywords: improvement; tigecycline; treatment; infection ... See more keywords
Diabetes Mellitus is Associated with Severe Infection and Mortality in Patients with COVID-19: A Systematic Review and Meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Medical Research"
DOI: 10.1016/j.arcmed.2020.07.005
Abstract: Abstract Background and Aim Currently, the number of patients with coronavirus disease 2019 (COVID-19) infection is increasing rapidly worldwide. In this study, we aimed to assess whether diabetes mellitus (DM) would increase the risk of… read more here.
Keywords: covid patients; infection; mortality; diabetes mellitus ... See more keywords
Correlation between severe infection and breast cancer metastases in the EORTC 10994/BIG 1-00 trial: Investigating innate immunity as a tumour suppressor in breast cancer.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of cancer"
DOI: 10.1016/j.ejca.2016.11.015
Abstract: BACKGROUND Breast cancer cells which express an innate immune signature regulated by interferon regulatory factor 7 (IRF7) have reduced metastatic potential. Infections can induce interferon signalling and may activate an anti-tumour immune response. We investigated… read more here.
Keywords: cancer; signature; breast cancer; severe infection ... See more keywords
Factors Associated With Severe COVID-19 Infection Among Persons of Different Ages Living in a Defined Midwestern US Population
Sign Up to like & getrecommendations! Published in 2021 at "Mayo Clinic Proceedings"
DOI: 10.1016/j.mayocp.2021.06.023
Abstract: Objective To identify risk factors associated with severe COVID-19 infection in a defined, Midwestern, U.S. population overall and within different age groups. Patients and Methods We used the Rochester Epidemiology Project research infrastructure to identify… read more here.
Keywords: risk; age; infection; covid infection ... See more keywords
Potential of the Prognostic Nutritional Index to Determine the Risk Factor for Severe Infection in Elderly Patients with Rheumatoid Arthritis.
Sign Up to like & getrecommendations! Published in 2022 at "Modern rheumatology"
DOI: 10.1093/mr/roac001
Abstract: OBJECTIVE To investigate the influence of nutritional status on severe infection complications in patients with rheumatoid arthritis (RA). METHODS This retrospective cohort study on 2,108 Japanese patients with RA treated at our hospital in April… read more here.
Keywords: group; elderly patients; severe infection; low pni ... See more keywords
P0940CLINICAL ASSOCIATION BETWEEN SEVERE INFECTION AND HYPOZINCEMIA IN INCIDENT PATIENTS ON HEMODIALYSIS
Sign Up to like & getrecommendations! Published in 2020 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaa142.p0940
Abstract: Hypozincemia can arise in patients with advanced chronic kidney disease (CKD) due to low protein intake and urinary or dialytic loss. Several studies have confirmed an association between hypozincemia and infection. Because infections comprise a… read more here.
Keywords: incident patients; infection; association; hypozincemia ... See more keywords
Multiplex proteomics as risk predictor of infection in patients treated with hemodialysis—A prospective multicenter study
Sign Up to like & getrecommendations! Published in 2021 at "Hemodialysis International"
DOI: 10.1111/hdi.12987
Abstract: Severe infection is a major problem in hemodialysis patients. Multiplex proteomics might reveal novel insights into disease mechanisms increasing the risk of infection and might also be used as a risk prediction tool. The aims… read more here.
Keywords: infection; hemodialysis; risk; infection patients ... See more keywords
Response to: ‘Risk of severe infection following rituximab and the efficacy of antimicrobial prophylaxis’ by Wallace et al
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-215036
Abstract: We thank Dr Wallace et al for their response to our recently published article ‘Trimethoprim–sulfamethoxazole prophylaxis prevents severe/life-threatening infections following rituximab in antineutrophil cytoplasm antibody-associated vasculitis’, highlighting some methodological limitations of our study.1 2 One… read more here.
Keywords: rituximab; infection; wallace; following rituximab ... See more keywords
COVID-19 infection and outcomes in a population-based cohort of 17 203 adults with intellectual disabilities compared with the general population
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Epidemiology and Community Health"
DOI: 10.1136/jech-2021-218192
Abstract: Background Adults with intellectual disabilities (ID) may be at higher risk of COVID-19 death. We compared COVID-19 infection, severe infection, mortality, case fatality and excess deaths, among adults with, and without, ID. Methods Adults with… read more here.
Keywords: covid infection; infection; mortality; severe infection ... See more keywords
Risk factors for severe infection and mortality in COVID-19 and monoclonal gammopathy of undetermined significance
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DOI: 10.1182/blood.2022017616
Abstract: Two Letters to Blood address the risks of COVID-19 in populations with precursors of hematological disease. In the first article, Miller and colleagues report on whether clonal hematopoiesis of intermediate potential (CHIP) is associated with… read more here.
Keywords: gammopathy undetermined; undetermined significance; mortality; severe infection ... See more keywords
Severe Infection of Pseudomonas aeruginosa during Eculizumab Therapy for Paroxysmal Nocturnal Hemoglobinuria
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DOI: 10.2169/internalmedicine.9151-17
Abstract: Eculizumab is the complement inhibitor administered to ameliorate intravascular hemolysis in paroxysmal nocturnal hemoglobinuria. Whether or not the inhibitory mechanism may also increase the susceptibility to non-Neisserial infection is unclear. A 73-year old woman presented… read more here.
Keywords: pseudomonas aeruginosa; infection; paroxysmal nocturnal; nocturnal hemoglobinuria ... See more keywords