Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2213317120
Abstract: Significance Due to increased exposure to various infectious diseases, including COVID-19, there is an urgent need for novel drugs that reduce mortality from severe infectious diseases. Although current drugs can suppress pathogen reproduction, immune cell… read more here.
Keywords: infectious diseases; permeability mortality; severe infectious; mortality ... See more keywords
Protection against severe infectious disease in the past
Sign Up to like & getrecommendations! Published in 2021 at "Pathogens and Global Health"
DOI: 10.1080/20477724.2021.1878443
Abstract: ABSTRACT Before the 20th century many deaths in England, and most likely a majority, were caused by infectious diseases. The focus here is on the biggest killers, plague, typhus, smallpox, tuberculosis, cholera, typhoid, dysentery, childhood… read more here.
Keywords: infectious disease; disease past; infectious diseases; severe infectious ... See more keywords
Predictors of mortality and poor outcome for patients with severe infectious encephalitis in the intensive care unit: a cross-sectional study
Sign Up to like & getrecommendations! Published in 2024 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-024-09312-1
Abstract: Background There are few thorough studies assessing predictors of severe encephalitis, despite the poor prognosis and high mortality associated with severe encephalitis. The study aims to evaluate the clinical predictors of mortality and poor outcomes… read more here.
Keywords: encephalitis; infectious encephalitis; mortality; intensive care ... See more keywords