Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2213317120
Abstract: Significance Due to increased exposure to various infectious diseases, including COVID-19, there is an urgent need for novel drugs that reduce mortality from severe infectious diseases. Although current drugs can suppress pathogen reproduction, immune cell… read more here.
Keywords: infectious diseases; permeability mortality; severe infectious; mortality ... See more keywords
Protection against severe infectious disease in the past
Sign Up to like & getrecommendations! Published in 2021 at "Pathogens and Global Health"
DOI: 10.1080/20477724.2021.1878443
Abstract: ABSTRACT Before the 20th century many deaths in England, and most likely a majority, were caused by infectious diseases. The focus here is on the biggest killers, plague, typhus, smallpox, tuberculosis, cholera, typhoid, dysentery, childhood… read more here.
Keywords: infectious disease; disease past; infectious diseases; severe infectious ... See more keywords