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   Articles with "severe influenza" as a keyword



The impact of obesity and timely antiviral administration on severe influenza outcomes among hospitalized adults

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recommendations! Published in 2018 at "Journal of Medical Virology"

DOI: 10.1002/jmv.24946

Abstract: Obesity was identified as a risk factor for severe influenza during the 2009 influenza A(H1N1)pandemic, but evidence of this association has been mixed since. Post‐pandemic antiviral treatment guidelines may have increased antiviral treatment among obese… read more here.

Keywords: admission; bmi; treatment; severe influenza ... See more keywords

Higher mortality of severe influenza patients with probable aspergillosis than those with and without other coinfections.

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recommendations! Published in 2017 at "Journal of the Formosan Medical Association = Taiwan yi zhi"

DOI: 10.1016/j.jfma.2017.06.002

Abstract: BACKGROUND/PURPOSE Aspergillus-associated infection might comprise up to 23-29% of severe influenza patients from the community throughout stay in an intensive care unit (ICU). In Taiwan, cases of severe influenza with aspergillosis are increasingly reported. Therefore,… read more here.

Keywords: aspergillosis; severe influenza; probable aspergillosis; mortality ... See more keywords
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Calculated risk: a new single-nucleotide polymorphism linked to severe influenza disease

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recommendations! Published in 2017 at "Nature Medicine"

DOI: 10.1038/nm.4383

Abstract: Clear links between human genes and susceptibility to influenza disease are scarce. A recent study uncovers a gene variant coupled to severe influenza, and shows how it hampers the expression of an antiviral gene that… read more here.

Keywords: severe influenza; calculated risk; influenza disease; risk new ... See more keywords
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Rates of Severe Influenza-Associated Outcomes Among Older Adults Living With Diabetes-Influenza Hospitalization Surveillance Network (FluSurv-NET), 2012-2017.

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recommendations! Published in 2022 at "Open forum infectious diseases"

DOI: 10.1093/ofid/ofac131

Abstract: Background Diabetes mellitus (DM) is common among older adults hospitalized with influenza, yet data are limited on the impact of DM on risk of severe influenza-associated outcomes. Methods We included adults aged ≥65 years hospitalized… read more here.

Keywords: influenza associated; older adults; surveillance; severe influenza ... See more keywords

Number of Influenza Risk Factors Informs an Adult's Increased Potential of Severe Influenza Outcomes: A Multiseason Cohort Study From 2015 to 2020

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recommendations! Published in 2024 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofae203

Abstract: Abstract Background While studies have evaluated factors influencing the risk of severe influenza outcomes, there is limited evidence on the additive impact of having multiple influenza risk factors and how this varies by age. Methods… read more here.

Keywords: number; severe influenza; influenza; influenza risk ... See more keywords

Effects of Baloxavir Marboxil Plus Neuraminidase Inhibitor vs Neuraminidase Inhibitor in High-risk Patients Hospitalized With Severe Influenza: A Post Hoc Analysis of the Flagstone Trial

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recommendations! Published in 2025 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofaf439

Abstract: Abstract Background Combining baloxavir with neuraminidase inhibitors (NAIs) has not demonstrated significant benefits in severe influenza. High-risk populations with impaired viral clearance may represent the optimal candidates for this combination treatment. Methods We conducted a… read more here.

Keywords: neuraminidase inhibitor; risk; antiviral group; severe influenza ... See more keywords
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The Extent of Aspergillosis in Critically Ill Patients With Severe Influenza Pneumonia: A Multicenter Cohort Study

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recommendations! Published in 2021 at "Critical Care Medicine"

DOI: 10.1097/ccm.0000000000004861

Abstract: Supplemental Digital Content is available in the text. OBJECTIVES: To determine the frequency and prognosis of invasive pulmonary aspergillosis in critically ill patients with severe influenza pneumonia. DESIGN: Retrospective multicenter cohort study. SETTING: Five French… read more here.

Keywords: ill patients; critically ill; invasive pulmonary; aspergillosis ... See more keywords

Concomitant severe influenza and cryptococcal infections

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recommendations! Published in 2019 at "Medicine"

DOI: 10.1097/md.0000000000015544

Abstract: Abstract Concomitant influenza and cryptococcal infections are rare. Herein, we describe an unusual case of an avian influenza A (H7N9) infection with several severe mixed bacterial infections and systemic super-infection with Cryptococcus neoformans presenting as… read more here.

Keywords: cryptococcal infections; severe influenza; infection; influenza cryptococcal ... See more keywords

Passive immune therapy and other immunomodulatory agents for the treatment of severe influenza: Systematic review and meta‐analysis

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recommendations! Published in 2019 at "Influenza and Other Respiratory Viruses"

DOI: 10.1111/irv.12699

Abstract: A range of immunomodulatory therapies have been proposed as adjuncts to conventional antivirals to suppress harmful inflammation during severe influenza infection. We conducted a systematic review to assess available data of the effect of adjunctive… read more here.

Keywords: passive immune; systematic review; severe influenza; immunomodulatory ... See more keywords

Ferroptosis-associated genes as candidate biomarkers for the identification of patients with severe influenza necessitating mechanical ventilation

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recommendations! Published in 2025 at "BMJ Open Respiratory Research"

DOI: 10.1136/bmjresp-2024-002557

Abstract: Background Ferroptotic cell death is a highly regulated process characterised by the iron-dependent accumulation of lipid peroxides on cell membranes. However, the role of ferroptosis-related genes (FRGs) in severe influenza is not well characterised. Methods… read more here.

Keywords: severe influenza; hub; ferroptosis; gene ... See more keywords

Severe Influenza A(H1N1) Virus Infection Complicated by Myositis, Refractory Rhabdomyolysis, and Compartment Syndrome

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recommendations! Published in 2019 at "Case Reports in Medicine"

DOI: 10.1155/2019/1540761

Abstract: Myositis is a rare and morbid complication of influenza infection that can rapidly progress to rhabdomyolysis with acute renal failure. Here, we describe a 35-year-old obese woman with severe influenza A(H1N1) virus infection complicated by… read more here.

Keywords: infection; severe influenza; influenza; rhabdomyolysis ... See more keywords