Homozygous mutations in DZIP1 can induce asthenoteratospermia with severe MMAF
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DOI: 10.1136/jmedgenet-2019-106479
Abstract: Background Asthenoteratospermia, one of the most common causes for male infertility, often presents with defective sperm heads and/or flagella. Multiple morphological abnormalities of the sperm flagella (MMAF) is one of the common clinical manifestations of… read more here.
Keywords: induce asthenoteratospermia; asthenoteratospermia; dzip1; severe mmaf ... See more keywords
Biallelic mutations in CFAP54 cause male infertility with severe MMAF and NOA.
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DOI: 10.1136/jmg-2022-108887
Abstract: BACKGROUND Spermatogenic impairments can lead to male infertility by different pathological conditions, such as multiple morphological abnormalities of the sperm flagella (MMAF) and non-obstructive azoospermia (NOA). Genetic factors are involved in impaired spermatogenesis. METHODS AND… read more here.
Keywords: mmaf; mmaf noa; male infertility; severe mmaf ... See more keywords