Identifying Important Clinical Symptoms in Children With Severe Neurological Impairment Using Parent-Reported Outcomes of Symptoms.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA pediatrics"
DOI: 10.1001/jamapediatrics.2020.2987
Abstract: This cross-sectional study evaluates whether the Parent-Reported Outcomes of Symptoms system identifies more symptoms than clinicians do among children with severe neurological impairment. read more here.
Keywords: reported outcomes; outcomes symptoms; parent reported; severe neurological ... See more keywords
Neuroinfluenza: evaluation of seasonal influenza associated severe neurological complications in children (a multicenter study)
Sign Up to like & getrecommendations! Published in 2017 at "Child's Nervous System"
DOI: 10.1007/s00381-017-3554-3
Abstract: PurposeAlthough influenza primarily affects the respiratory system, in some cases, it can cause severe neurological complications. Younger children are especially at risk. Pediatric literature is limited on the diagnosis, treatment, and prognosis of influenza-related neurological… read more here.
Keywords: influenza related; severe neurological; seasonal influenza; influenza infection ... See more keywords
Asymmetrical 3D Nanoceria Channel for Severe Neurological Defect Regeneration
Sign Up to like & getrecommendations! Published in 2019 at "iScience"
DOI: 10.1016/j.isci.2019.01.013
Abstract: Summary Inflammation and oxidative stress are major problems in peripheral nerve injury. Nanoceria can manipulate antioxidant factor expression, stimulate angiogenesis, and assist in axonal regeneration. We fabricate collagen/nanoceria/polycaprolactone (COL/NC/PCL) conduit by asymmetrical three-dimensional manufacture and… read more here.
Keywords: asymmetrical nanoceria; neurological defect; regeneration; severe neurological ... See more keywords
Severe neurological disorders and refractory aspergillosis in an adolescent treated by vincristine and voriconazole
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.12603
Abstract: Voriconazole and vincristine are major therapeutics in paediatric haematology. However, the risk‐benefit ratio of the treatment of invasive aspergillosis with voriconazole in patients receiving vincristine‐based chemotherapy remains unclear. read more here.
Keywords: aspergillosis; refractory aspergillosis; disorders refractory; severe neurological ... See more keywords
P131 ‘Severe neurological impairment’ – does the term define an agreed cohort for study?
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2019-epa.486
Abstract: Background Severe Neurological Impairment (SNI) is a term commonly used in the medical literature. There is no agreed definition of SNI. This limits opportunities for research into healthcare needs, treatment opportunities, resource planning and outcome.… read more here.
Keywords: definition; term; severe neurological; neurological impairment ... See more keywords
The Impact of Caring for Children With Severe Neurological Impairment on Clinicians
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pediatrics"
DOI: 10.1177/00099228221099135
Abstract: Clinicians face many challenges in caring for children with severe neurological impairment (SNI). This study aimed to understand expert clinician perspectives on the personal impact of caring for children with SNI to highlight the challenges… read more here.
Keywords: severe neurological; children severe; caring children; neurological impairment ... See more keywords
10-year follow-up of congenital cytomegalovirus infection complicated with severe neurological findings in infancy: a case report
Sign Up to like & getrecommendations! Published in 2018 at "BMC Pediatrics"
DOI: 10.1186/s12887-018-1348-8
Abstract: BackgroundCongenital cytomegalovirus (cCMV) infection leads to sensorineural hearing loss (SNHL) and neurodevelopmental delays. However, the long-term outcomes of cCMV infection with severe neurological manifestations in infancy remain unclear.Case presentationThe patient was a one-month-old girl visited… read more here.
Keywords: hearing loss; infection; cytomegalovirus; severe neurological ... See more keywords
Neurological manifestations in thrombotic microangiopathy: Imaging features, risk factors and clinical course
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0272290
Abstract: Background and purpose Thrombotic microangiopathy (TMA) is a group of microvascular occlusive disorders that presents with neurological involvement in up to 87% of the cases. Although the central nervous system (CNS) is an important target… read more here.
Keywords: thrombotic microangiopathy; manifestations thrombotic; clinical course; severe neurological ... See more keywords
Novel ELAC2 Mutations in Individuals Presenting with Variably Severe Neurological Disease in the Presence or Absence of Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2023 at "Life"
DOI: 10.3390/life13020445
Abstract: Transcription of mitochondrial DNA generates long polycistronic precursors whose nucleolytic cleavage yields the individual mtDNA-encoded transcripts. In most cases, this cleavage occurs at the 5′- and 3′-ends of tRNA sequences by the concerted action of… read more here.
Keywords: novel elac2; cardiomyopathy; variably severe; severe neurological ... See more keywords
Pembrolizumab-Related Side Effects: Acute Renal Failure and Severe Neurological Toxicity
Sign Up to like & getrecommendations! Published in 2022 at "Medicina"
DOI: 10.3390/medicina58020209
Abstract: Immunotherapy with immune checkpoint inhibitors represents nowadays a marked improvement in cancer treatment. Nevertheless, they can cause severe toxicities that put the patient at high risk, often requiring aggressive treatment. We present the case of… read more here.
Keywords: related side; renal failure; treatment; pembrolizumab related ... See more keywords
Severe neurological manifestations of influenza during 2018-2019 influenza season: Case series of 13 pediatric patients.
Sign Up to like & getrecommendations! Published in 2021 at "Archivos argentinos de pediatria"
DOI: 10.5546/aap.2021.eng.e142
Abstract: Influenza is mostly associated with the respiratory tract system, especially in the winter season. Various neurological complications could occur due to influenza infection. Pediatric patients who had severe neurological manifestations due to influenza infection from… read more here.
Keywords: severe neurological; neurological manifestations; influenza season; pediatric patients ... See more keywords