Human Suprapatellar Fat Pad-Derived Mesenchymal Stem Cells Induce Chondrogenesis and Cartilage Repair in a Model of Severe Osteoarthritis
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DOI: 10.1155/2017/4758930
Abstract: Cartilage degeneration is associated with degenerative bone and joint processes in severe osteoarthritis (OA). Spontaneous cartilage regeneration is extremely limited. Often the treatment consists of a partial or complete joint implant. Adipose-derived stem cell (ASC)… read more here.
Keywords: suprapatellar fat; suprapatellar derived; severe osteoarthritis; stem ... See more keywords
A phase I–II controlled randomized trial using a promising novel cell-free formulation for articular cartilage regeneration as treatment of severe osteoarthritis of the knee
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DOI: 10.1186/s40001-018-0349-2
Abstract: BackgroundA promising novel cell-free bioactive formulation for articular cartilage regeneration, called BIOF2, has recently been tested in pre-clinical trials. The aim of the present study was to evaluate the efficacy and safety of BIOF2 for… read more here.
Keywords: treatment; articular cartilage; severe osteoarthritis; osteoarthritis knee ... See more keywords
Metabolomic Analysis of Severe Osteoarthritis in a Spanish Population of Women Compared to Healthy and Osteoporotic Subjects
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DOI: 10.3390/metabo12080677
Abstract: Bone pathologies such as osteoporosis (OTP) and osteoarthritis (OA) are rising in incidence with the worldwide rise in life expectancy. The diagnosis is usually obtained using imaging techniques such as densitometry, but with both being… read more here.
Keywords: fracture; osteoarthritis; severe osteoarthritis; analysis ... See more keywords