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Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.04.001
Abstract: The human placenta and its specialized cytotrophoblasts rapidly develop, have a compressed lifespan, govern pregnancy outcomes, and program the offspring's health. Understanding the molecular underpinnings of these behaviors informs development and disease. Profiling the extraembryonic…
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Keywords:
placental disease;
placental cytotrophoblast;
cytotrophoblast epigenome;
disease ... See more keywords
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Published in 2021 at "Journal of Lipid Research"
DOI: 10.1016/j.jlr.2021.100118
Abstract: Preeclampsia is a pregnancy-specific syndrome characterized by hypertension and proteinuria after 20 weeks of gestation. However, it is not well understood what lipids are involved in the development of this condition, and even less is…
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Keywords:
blood lipidome;
pathogenesis;
preeclampsia;
lipidome indicative ... See more keywords
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Published in 2017 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2017.03.003
Abstract: OBJECTIVE To examine the recovery from severe Preeclampsia toxemia (PET) in women treated with magnesium sulfate (MgSO4) during the first 24h postpartum as reflected by the changes in various clinical and laboratory markers. STUDY DESIGN…
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Keywords:
recovery;
clinical laboratory;
laboratory markers;
severe preeclampsia ... See more keywords
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Published in 2017 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2017.04.002
Abstract: MicroRNA (miRNA) expression has not been studied during placentation in pregnancies that develop preeclampsia, when it likely manifests. In this pilot study, miRNA expression in late first trimester placenta from four pregnancies that developed severe…
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Keywords:
pilot study;
trimester placenta;
preeclampsia;
first trimester ... See more keywords
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Published in 2019 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2019.05.017
Abstract: Previous studies have suggested that altered miRNA expression in the placenta is associated with preeclampsia. The aim of this study was to investigate the expression of miR-424 in placental samples of severe preeclampsia (sPE) and…
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Keywords:
expression;
placenta associated;
mir 424;
severe preeclampsia ... See more keywords
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Published in 2019 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2019.11.002
Abstract: BACKGROUND The present study aims to explore the possible mechanisms of Hippo-YAP1 signaling pathway in the development of severe preeclampsia (sPE). METHODS A total of 14 pregnancies complicated with severe preeclampsia as well as 14…
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Keywords:
yap1;
hippo yap1;
mst;
group ... See more keywords
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Published in 2020 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2020.04.003
Abstract: OBJECTIVES Posterior reversible encephalopathy syndrome (PRES) is the neuroradiological appearance of eclampsia. This study was conducted to understand the neuroradiological aspects of severe preeclampsia by recognition of PRES. We hypothesized that posterior reversible encephalopathy syndrome…
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Keywords:
encephalopathy syndrome;
posterior reversible;
preeclampsia;
eclampsia ... See more keywords
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Published in 2021 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2021.07.240
Abstract: OBJECTIVE Globally, preeclampsia is a significant contributor to adverse maternal outcomes. Once women develop eclampsia, they face considerable risks especially in countries with limited resources to deal with such a life-threatening complication. This study was…
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Keywords:
central hospital;
determinants eclampsia;
study;
severe preeclampsia ... See more keywords
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Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82733-z
Abstract: Preeclampsia is a pregnancy-specific multisystem disorder and a leading cause of maternal and perinatal morbidity and mortality. The exact pathogenesis of this multifactorial disease remains poorly defined. We applied proteomics analysis on maternal blood samples…
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Keywords:
onset severe;
early onset;
analysis;
preeclampsia ... See more keywords
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Published in 2023 at "American journal of perinatology"
DOI: 10.1055/a-2097-1212
Abstract: OBJECTIVE The objective of this study is to examine risk factors and adverse outcomes related to preeclampsia with severe features complicated by pulmonary edema. STUDY DESIGN This is a nested case-control study of all patients…
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Keywords:
edema;
control;
pulmonary edema;
study ... See more keywords
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Published in 2022 at "American journal of perinatology"
DOI: 10.1055/s-0042-1748524
Abstract: OBJECTIVE  The aim of the study is to evaluate the association between the amount of proteinuria at the time of diagnosis of preeclampsia with severe features (severe preeclampsia [SPE]) and duration of expectant management (EM)…
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Keywords:
amount proteinuria;
preeclampsia;
duration;
proteinuria ... See more keywords