Challenges and opportunities for pediatric severe TBI—review of the evidence and exploring a way forward
Sign Up to like & getrecommendations! Published in 2017 at "Child's Nervous System"
DOI: 10.1007/s00381-017-3530-y
Abstract: Traumatic brain injury (TBI) is a leading killer of children in the developed and developing world. Despite evidence-based guidelines and several recent clinical trials, the progress in developing best practices for children with severe TBI… read more here.
Keywords: challenges opportunities; pediatric severe; opportunities pediatric; severe tbi ... See more keywords
Statewide Trends in ICP Monitor Use in 36,915 Patients with Severe TBI in a Mature Trauma State over the past 18 years.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2019.06.025
Abstract: OBJECTIVE While intracranial pressure-guided therapy has been the mainstay of treatment of patients with severe traumatic brain injury (TBI), recent data has questioned its efficacy. Our goal is to demonstrate the trends in compliance to… read more here.
Keywords: patients severe; severe tbi; mature trauma; icp monitor ... See more keywords
The cortical and subcortical substrates of quality of life through substrates of self-awareness and executive functions, in chronic moderate-to-severe TBI
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DOI: 10.1080/02699052.2022.2034960
Abstract: ABSTRACT Background Moderate-to-severe traumatic brain injury (TBI) follows a chronic neuro-psychological sequelae, interfering with quality of life (QOL). Objective To investigate the chronic effects of moderate-to-severe TBI as expressed by greater atrophy in specific regions-of-interest… read more here.
Keywords: tbi; regions interest; severe tbi; executive functions ... See more keywords
COVID-19's impact on a community-based physical activity program for adults with moderate-to-severe TBI.
Sign Up to like & getrecommendations! Published in 2023 at "Disability and rehabilitation"
DOI: 10.1080/09638288.2023.2212180
Abstract: PURPOSE Physical activity (PA) is proposed for long-term problems after traumatic brain injury (TBI) with mood, quality of life, and participation. However, COVID-19 mitigation strategies resulted in widespread closures of community-based fitness centres, including one… read more here.
Keywords: tbi; severe tbi; physical activity; program ... See more keywords
Goal-directed platelet transfusions correct platelet dysfunction and may improve survival in patients with severe traumatic brain injury
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000002047
Abstract: BACKGROUND Platelet dysfunction, defined as adenosine diphosphate inhibition greater than 60% on thromboelastogram, is an independent predictor of increased mortality in patients with severe traumatic brain injury (TBI). We changed our practice to transfuse platelets… read more here.
Keywords: patients severe; platelet transfusion; platelet dysfunction; severe tbi ... See more keywords
Early diagnosis of mortality using admission CT perfusion in severe traumatic brain injury patients (ACT-TBI): protocol for a prospective cohort study
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Open"
DOI: 10.1136/bmjopen-2020-047305
Abstract: Introduction Severe traumatic brain injury (TBI) is a catastrophic neurological condition with significant economic burden. Early in-hospital mortality ( read more here.
Keywords: traumatic brain; admission; severe traumatic; severe tbi ... See more keywords
PREdiction and Diagnosis using Imaging and Clinical biomarkers Trial in Traumatic Brain Injury (PREDICT-TBI) study protocol: an observational, prospective, multicentre cohort study for the prediction of outcome in moderate-to-severe TBI
Sign Up to like & getrecommendations! Published in 2023 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-067740
Abstract: Introduction Traumatic brain injury (TBI) is a heterogeneous condition with a broad spectrum of injury severity, pathophysiological processes and variable outcomes. For moderate-to-severe TBI survivors, recovery is often protracted and outcomes can range from total… read more here.
Keywords: tbi; severe tbi; prediction; moderate severe ... See more keywords
The epidemiology of moderate and severe traumatic brain injury in Central Norway.
Sign Up to like & getrecommendations! Published in 2023 at "Neuroepidemiology"
DOI: 10.1159/000529072
Abstract: INTRODUCTION Few studies account for prehospital deaths when estimating incidence and mortality rates of moderate and severe traumatic brain injury (msTBI). In a population-based study, covering both urban and rural areas, including also prehospital deaths,… read more here.
Keywords: mortality rates; incidence; severe tbi; incidence mortality ... See more keywords
Functional Outcomes 6 Months After Severe Traumatic Brain Injury Following Admission Into Intensive Care Unit: A Cohort Study in Two Tertiary Hospitals
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Nursing Research"
DOI: 10.1177/1054773818767551
Abstract: Severe traumatic brain injury (TBI) survivors show physical and functional improvements but continue to have cognitive and psychosocial problems throughout recovery. However, the functional outcome of severe TBI in Malaysia is unknown. The objective of… read more here.
Keywords: traumatic brain; severe traumatic; severe tbi; functional outcomes ... See more keywords
Risk of hospitalization with neurodegenerative disease after moderate-to-severe traumatic brain injury in the working-age population: A retrospective cohort study using the Finnish national health registries
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Medicine"
DOI: 10.1371/journal.pmed.1002316
Abstract: Background Previous epidemiological studies suggest that working-aged persons with a history of moderate-to-severe traumatic brain injury (TBI) may have an increased risk for developing neurodegenerative disease (NDD) while persons with a history of mild TBI… read more here.
Keywords: risk; disease; severe tbi; study ... See more keywords
Quantitative Proteomics Reveals the Dynamic Pathophysiology Across Different Stages in a Rat Model of Severe Traumatic Brain Injury
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2021.785938
Abstract: Background Severe traumatic brain injury (TBI) has become a global health problem and causes a vast worldwide societal burden. However, distinct mechanisms between acute and subacute stages have not been systemically revealed. The present study… read more here.
Keywords: traumatic brain; severe tbi; brain; severe traumatic ... See more keywords