Pediatric moderate and severe traumatic brain injury – A national, population-based cohort study
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Trauma and Emergency Surgery"
DOI: 10.1007/s00068-025-02960-1
Abstract: This study aims to investigate the epidemiological characteristics, injury mechanisms, and clinical outcomes of children with moderate and severe traumatic brain injury (TBI), using population-based data from a national trauma registry. This nationwide observational cohort… read more here.
Keywords: moderate severe; severe tbi; injury; population based ... See more keywords
Challenges and opportunities for pediatric severe TBI—review of the evidence and exploring a way forward
Sign Up to like & getrecommendations! Published in 2017 at "Child's Nervous System"
DOI: 10.1007/s00381-017-3530-y
Abstract: Traumatic brain injury (TBI) is a leading killer of children in the developed and developing world. Despite evidence-based guidelines and several recent clinical trials, the progress in developing best practices for children with severe TBI… read more here.
Keywords: challenges opportunities; pediatric severe; opportunities pediatric; severe tbi ... See more keywords
Statewide Trends in ICP Monitor Use in 36,915 Patients with Severe TBI in a Mature Trauma State over the past 18 years.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2019.06.025
Abstract: OBJECTIVE While intracranial pressure-guided therapy has been the mainstay of treatment of patients with severe traumatic brain injury (TBI), recent data has questioned its efficacy. Our goal is to demonstrate the trends in compliance to… read more here.
Keywords: patients severe; severe tbi; mature trauma; icp monitor ... See more keywords
Naming Ability in the Chronic Phase of Moderate-Severe Traumatic Brain Injury.
Sign Up to like & getrecommendations! Published in 2024 at "American journal of speech-language pathology"
DOI: 10.1044/2024_ajslp-23-00249
Abstract: INTRODUCTION Naming difficulties are commonly reported in the acute and subacute stages of recovery of traumatic brain injury (TBI) and across severity levels. Previous studies, however, have used samples of mixed chronicity (acute and chronic)… read more here.
Keywords: moderate severe; traumatic brain; severe tbi; brain injury ... See more keywords
The cortical and subcortical substrates of quality of life through substrates of self-awareness and executive functions, in chronic moderate-to-severe TBI
Sign Up to like & getrecommendations! Published in 2022 at "Brain Injury"
DOI: 10.1080/02699052.2022.2034960
Abstract: ABSTRACT Background Moderate-to-severe traumatic brain injury (TBI) follows a chronic neuro-psychological sequelae, interfering with quality of life (QOL). Objective To investigate the chronic effects of moderate-to-severe TBI as expressed by greater atrophy in specific regions-of-interest… read more here.
Keywords: tbi; regions interest; severe tbi; executive functions ... See more keywords
COVID-19's impact on a community-based physical activity program for adults with moderate-to-severe TBI.
Sign Up to like & getrecommendations! Published in 2023 at "Disability and rehabilitation"
DOI: 10.1080/09638288.2023.2212180
Abstract: PURPOSE Physical activity (PA) is proposed for long-term problems after traumatic brain injury (TBI) with mood, quality of life, and participation. However, COVID-19 mitigation strategies resulted in widespread closures of community-based fitness centres, including one… read more here.
Keywords: tbi; severe tbi; physical activity; program ... See more keywords
Goal-directed platelet transfusions correct platelet dysfunction and may improve survival in patients with severe traumatic brain injury
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000002047
Abstract: BACKGROUND Platelet dysfunction, defined as adenosine diphosphate inhibition greater than 60% on thromboelastogram, is an independent predictor of increased mortality in patients with severe traumatic brain injury (TBI). We changed our practice to transfuse platelets… read more here.
Keywords: patients severe; platelet transfusion; platelet dysfunction; severe tbi ... See more keywords
Recovery after moderate to severe TBI and factors influencing functional outcome: What you need to know
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000004305
Abstract: ABSTRACT Traumatic brain injury (TBI) represents a major cause of death and disability, significantly impacting the lives of 2.5 million people annually in the United States. Long-term natural history studies have clarified that functional recovery… read more here.
Keywords: history; severe tbi; outcome; natural history ... See more keywords
Daily quetiapine after severe TBI improves learning and memory
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000004400
Abstract: BACKGROUND Traumatic brain injury (TBI) induces cognitive deficits driven by neuroinflammation and cerebral edema. The commonly used atypical antipsychotic, quetiapine (QTP), has been recently shown to improve post-TBI outcomes. We hypothesized that QTP would thereby… read more here.
Keywords: severe tbi; spatial learning; tbi; daily quetiapine ... See more keywords
Early diagnosis of mortality using admission CT perfusion in severe traumatic brain injury patients (ACT-TBI): protocol for a prospective cohort study
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Open"
DOI: 10.1136/bmjopen-2020-047305
Abstract: Introduction Severe traumatic brain injury (TBI) is a catastrophic neurological condition with significant economic burden. Early in-hospital mortality ( read more here.
Keywords: traumatic brain; admission; severe traumatic; severe tbi ... See more keywords
PREdiction and Diagnosis using Imaging and Clinical biomarkers Trial in Traumatic Brain Injury (PREDICT-TBI) study protocol: an observational, prospective, multicentre cohort study for the prediction of outcome in moderate-to-severe TBI
Sign Up to like & getrecommendations! Published in 2023 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-067740
Abstract: Introduction Traumatic brain injury (TBI) is a heterogeneous condition with a broad spectrum of injury severity, pathophysiological processes and variable outcomes. For moderate-to-severe TBI survivors, recovery is often protracted and outcomes can range from total… read more here.
Keywords: tbi; severe tbi; prediction; moderate severe ... See more keywords