Severe thrombocytopenia as a predictor of survival and response to hypomethylating agents in myelodysplastic syndromes: A Latin‐American cohort of 212 patients
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Hematology"
DOI: 10.1002/ajh.25987
Abstract: AUTHOR CONTRIBUTIONS Contribution: K.B.B.P., principal investigator of this trial, conceived and designed the study; E.V.D.P., M.T.D. and G.O.D. were sub-investigators. KBBP and EVDP contributed to the data interpretation and drafted the manuscript. K.B.B.P., E.V.D.P., A.B.P.L.,… read more here.
Keywords: thrombocytopenia predictor; predictor survival; severe thrombocytopenia; survival response ... See more keywords
The management and outcomes of patients with myelodysplastic syndrome with persistent severe thrombocytopenia: An observational single centre registry study.
Sign Up to like & getrecommendations! Published in 2019 at "Leukemia research"
DOI: 10.1016/j.leukres.2018.12.002
Abstract: BACKGROUND Severe thrombocytopenia affects 10% of patients with myelodysplastic syndrome (MDS) and is associated with poor outcomes. The role for prophylactic platelet transfusions in the outpatient setting is unknown. OBJECTIVE/METHODS To audit treatments, bleeding rates,… read more here.
Keywords: thrombocytopenia; patients myelodysplastic; severe thrombocytopenia; myelodysplastic syndrome ... See more keywords
Management and outcomes of cancer patients with venous thromboembolism presenting with thrombocytopenia.
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DOI: 10.1016/j.thromres.2020.07.021
Abstract: INTRODUCTION Treatment of venous thromboembolism (VTE) in cancer patients with thrombocytopenia is challenging due to perceived higher risk of bleeding. MATERIAL AND METHODS We used the RIETE registry to compare the 10- and 30-day outcomes… read more here.
Keywords: venous thromboembolism; severe thrombocytopenia; cancer; cancer patients ... See more keywords
Development and validation of a prediction model for in-hospital mortality of patients with severe thrombocytopenia
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DOI: 10.1038/s41598-022-10438-y
Abstract: Risk stratification and prognosis evaluation of severe thrombocytopenia are essential for clinical treatment and management. Currently, there is currently no reliable predictive model to identify patients at high risk of severe thrombocytopenia. This study aimed… read more here.
Keywords: hospital mortality; severe thrombocytopenia; nomogram model; model ... See more keywords
Labor epidural analgesia with severe thrombocytopenia
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DOI: 10.1080/08998280.2021.1961551
Abstract: Abstract Thrombocytopenia in pregnancy could potentially lead to epidural hematoma and associated morbidity when neuraxial anesthesia is performed. We present a case of a 24-year-old parturient, who was otherwise healthy and without prior thrombocytopenia, who… read more here.
Keywords: severe thrombocytopenia; thrombocytopenia; labor epidural; analgesia severe ... See more keywords
Using first-contact serum ferritin to predict severe thrombocytopenia in dengue patients: determination and validation in independent cohorts
Sign Up to like & getrecommendations! Published in 2022 at "Infectious Diseases"
DOI: 10.1080/23744235.2022.2032823
Abstract: Abstract Background Severe thrombocytopenia and associated haemorrhage are dreaded complications of dengue fever. The identification of a biomarker that can predict, or rule out, its subsequent development can help identify at-risk individuals. Methods 200 dengue… read more here.
Keywords: ferritin; validation; severe thrombocytopenia; predict ... See more keywords
The atypical lymphocyte count: a novel predictive factor for severe thrombocytopenia related to dengue.
Sign Up to like & getrecommendations! Published in 2020 at "Transactions of the Royal Society of Tropical Medicine and Hygiene"
DOI: 10.1093/trstmh/trz128
Abstract: BACKGROUND Early identification of patients at risk of severe dengue disease (DD) is critical to guide its management. We evaluated whether the atypical lymphocyte count (ALC), generated from the Sysmex automated full blood count analyzer,… read more here.
Keywords: atypical lymphocyte; lymphocyte count; severe thrombocytopenia; day ... See more keywords
Predictors of Severe Thrombocytopenia Secondary to Peginterferon Alfa-2a Treatment in Subjects With Hepatitis C Virus Infection
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DOI: 10.1097/mjt.0000000000000356
Abstract: In this study, we aim to identify patient characteristics that predict severe thrombocytopenia induced by peginterferon alfa-2a in hepatitis C virus–infected patients. Demographic, clinical, and genetic data collected from patients with chronic hepatitis C virus… read more here.
Keywords: thrombocytopenia; peginterferon alfa; severe thrombocytopenia; hepatitis virus ... See more keywords
A Severe Case of Murine Typhus Presenting With Anemia and Severe Thrombocytopenia
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DOI: 10.1097/mph.0000000000001024
Abstract: We discuss a child with severe thrombocytopenia and mild anemia admitted to the Hematology service who quickly deteriorated to a life-threatening state. However, once rickettsial disease was considered in the differential diagnosis and empiric doxycycline… read more here.
Keywords: anemia; hematology; severe thrombocytopenia; murine typhus ... See more keywords
Variables affecting the presence of occult cerebral microbleeds and subsequent spontaneous intracranial haemorrhage in adult patients with severe thrombocytopenia
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DOI: 10.1111/bjh.17500
Abstract: Severe thrombocytopenia (platelet count < 20 9 10/l) could cause spontaneous intracranial haemorrhage (ICH). Platelet count has been shown to be a poor predictor of haemorrhage in patients with haematological disorders. Cerebral microbleeds (CMBs) are… read more here.
Keywords: patients severe; haemorrhage; severe thrombocytopenia; spontaneous intracranial ... See more keywords
Severe thrombocytopenia in the setting of anaemia: The role of iron‐deficiency revisited
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DOI: 10.1111/jpc.16256
Abstract: Severe thrombocytopenia in the setting of anaemia: The role of iron-deficiency revisited Cyrus Ghaznavi, Sabat Ameen, Meghana Srinivas, Eric Duncavage and Surbhi Saini 3 Medical Education Program, Department of Pathology and Immunology, Washington University School… read more here.
Keywords: anaemia role; role iron; severe thrombocytopenia; setting anaemia ... See more keywords