Delayed Initiation of Rescue Therapy Associated with Increased Length of Stay in Acute Severe Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2022 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-022-07490-z
Abstract: Reducing hospitalization length of stay (LOS) for acute severe ulcerative colitis (ASUC) will reduce healthcare costs, mitigate hospitalization-associated risks (e.g., venous thromboembolism), and improve quality of life. A chart review was performed of all adult… read more here.
Keywords: therapy; acute severe; initiation; severe ulcerative ... See more keywords
Acute severe ulcerative colitis: management advice for internal medicine and emergency physicians
Sign Up to like & getrecommendations! Published in 2021 at "Internal and Emergency Medicine"
DOI: 10.1007/s11739-021-02704-0
Abstract: Acute severe ulcerative colitis is a medical emergency that warrants in-patient management. This is best served within a multidisciplinary team setting in specialised centres or with expert consultation. Intravenous corticosteroids remain the cornerstone in the… read more here.
Keywords: medicine; acute severe; severe ulcerative; management ... See more keywords
Efficacy and Safety of Abrilumab in a Randomized, Placebo-Controlled Trial for Moderate-to-Severe Ulcerative Colitis.
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology"
DOI: 10.1053/j.gastro.2018.11.035
Abstract: BACKGROUND & AIMS The α4β7 integrin is a validated target in inflammatory bowel disease. This randomized, phase 2b, placebo-controlled, double-blind study evaluated the efficacy and safety of the anti-α4β7 antibody abrilumab in patients with moderate-to-severe… read more here.
Keywords: response; severe ulcerative; ulcerative colitis; placebo ... See more keywords
Management of acute severe ulcerative colitis in children.
Sign Up to like & getrecommendations! Published in 2017 at "Seminars in pediatric surgery"
DOI: 10.1053/j.sempedsurg.2017.10.006
Abstract: The incidence of pediatric-onset ulcerative colitis (UC) is rising. Children often present with a more severe disease phenotype as compared to adults with over a third requiring hospitalization for the management of acute severe ulcerative… read more here.
Keywords: acute severe; severe ulcerative; management acute; colitis ... See more keywords
Positioning ustekinumab in moderate-to-severe ulcerative colitis: new kid on the block
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2020.1727437
Abstract: ABSTRACT Introduction: Ulcerative colitis (UC) is a chronic relapsing disorder of the colonic tract. Dysregulated innate and adaptive immune pathways contribute to intestinal inflammation in IBD, and cytokines, including IL-12 and IL-23, play a key… read more here.
Keywords: positioning ustekinumab; ustekinumab moderate; severe ulcerative; ulcerative colitis ... See more keywords
P489 Rescue treatment with original versus biosimilar infliximab in biologic-naïve patients with moderate-severe Ulcerative Colitis and corticosteroid failure
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjab076.612
Abstract: Infliximab is effective as rescue therapy in moderate-severe Ulcerative Colitis (UC). Subsequently, a biosimilar of infliximab has been approved for the same indications, as its effectiveness is considered similar to the original infliximab. Our aim… read more here.
Keywords: moderate severe; severe ulcerative; ulcerative colitis; infliximab ... See more keywords
Hyperbaric Oxygen as Successful Monotherapy for a Severe Ulcerative Colitis Flare.
Sign Up to like & getrecommendations! Published in 2022 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izac141
Abstract: This report presents a case of severe ulcerative colitis treated with hyperbaric oxygen as successful monotherapy. read more here.
Keywords: oxygen successful; severe ulcerative; hyperbaric oxygen; ulcerative colitis ... See more keywords
SARS-CoV-2 (COVID-19) pneumonia patient treated with two doses of infliximab within 2 weeks for acute severe ulcerative colitis
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000028722
Abstract: Abstract Rationale: The ongoing coronavirus pandemic has caused severe acute respiratory syndrome, posing a significant challenge for patients receiving immunotherapy for immune-mediated inflammatory diseases. As of January 2022, immunosuppressants such as tumor necrosis factor inhibitors… read more here.
Keywords: severe ulcerative; patient; ulcerative colitis; acute severe ... See more keywords
Change in paradigm: impact of an IBD medical home on the outpatient management of acute severe ulcerative colitis
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Case Reports"
DOI: 10.1136/bcr-2019-230491
Abstract: A 72-year-old man presents with acute severe ulcerative colitis (ASUC), initially partially responsive to intravenous steroids and infliximab over a 3-day hospital stay. Following discharge and over the course of 15 days, his care was… read more here.
Keywords: medical home; acute severe; ulcerative colitis; severe ulcerative ... See more keywords
Development and Improvement of Simple Colonic Mucosal Ulcer during Treatment of Severe Ulcerative Colitis with Tacrolimus
Sign Up to like & getrecommendations! Published in 2017 at "Case Reports in Gastroenterology"
DOI: 10.1159/000456605
Abstract: Diarrhea, melena, and lower abdominal pain developed in a male in his 20s and colonoscopy showed pancolitis-type severe ulcerative colitis (UC). Treatment was initiated with 4,000 mg of 5-aminosalicylic acid and 60 mg/day of prednisolone,… read more here.
Keywords: improvement simple; treatment; severe ulcerative; ulcerative colitis ... See more keywords
Colonic Dilatation Complicating Acute Severe Ulcerative Colitis Managed Successfully with Accelerated Infliximab Dosing
Sign Up to like & getrecommendations! Published in 2023 at "Case Reports in Gastroenterology"
DOI: 10.1159/000529152
Abstract: Abstract Lately, emerging data suggest an association between the development of inflammatory bowel disease and anti-interleukin-17 therapy. Megacolon is a life-threatening complication of acute severe ulcerative colitis (ASUC), but its treatment has not yet been… read more here.
Keywords: accelerated infliximab; colonic dilatation; severe ulcerative; ulcerative colitis ... See more keywords