Molecular investigations into the unfoldase action of severing enzymes on microtubules
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DOI: 10.1002/cm.21606
Abstract: Microtubule (MT)‐associated proteins regulate the dynamic behavior of MTs during cellular processes. MT severing enzymes are the associated proteins which destabilize MTs by removing subunits from the lattice. One model for how severing enzymes remove… read more here.
Keywords: enzymes microtubules; action severing; severing enzymes; unfoldase action ... See more keywords
Computer simulation reveals the effect of severing enzymes on dynamic and stabilized microtubules
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DOI: 10.1088/1478-3975/acc301
Abstract: Microtubule (MT) severing enzymes Katanin and Spastin cut the MT into smaller fragments and are being studied extensively using in-vitro experiments due to their crucial role in different cancers and neurodevelopmental disorders. It has been… read more here.
Keywords: tubulin mass; severing enzyme; severing enzymes; effect severing ... See more keywords