Investigating the sex-linked mechanisms of Hirschsprung disease using mouse models
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.023
Abstract: Hirschsprung disease (HSCR) is a complex developmental disorder characterised by the lack of enteric neurons in distal portions of the gut. Importantly, HSCR presents a dramatic sex bias with at least 4 times more males… read more here.
Keywords: mouse models; sex bias; hirschsprung disease; sex ... See more keywords
Crosstalk between Notch and FSH signaling, key to ovarian cancer progression
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.024
Abstract: Hirschsprung disease (HSCR) is a complex developmental disorder characterised by the lack of enteric neurons in distal portions of the gut. Importantly, HSCR presents a dramatic sex bias with at least 4 times more males… read more here.
Keywords: sex bias; notch fsh; crosstalk notch; sex ... See more keywords
A deleterious recessive mutation in NUAK2 causes absence of brain in humans
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.025
Abstract: Hirschsprung disease (HSCR) is a complex developmental disorder characterised by the lack of enteric neurons in distal portions of the gut. Importantly, HSCR presents a dramatic sex bias with at least 4 times more males… read more here.
Keywords: deleterious recessive; sex bias; recessive mutation; sex ... See more keywords
Sex Bias in Interventional Clinical Trials.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of women's health"
DOI: 10.1089/jwh.2017.6873
Abstract: INTRODUCTION Prior studies have shown that sex bias exists with subject enrollment in clinical trials, with more men being enrolled than women. The objective of this study was to identify if sex bias continues to… read more here.
Keywords: phase; sex bias; male female; sex ... See more keywords
Sex bias in research animals
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.364.6443.846-p
Abstract: Neuroscience Owing to perceptions about the natural variation caused by hormonal cycling, female animals have largely been excluded from preclinical research in various disciplines, particularly neuroscience. However, male rodents exhibit as much behavioral and hormonal… read more here.
Keywords: bias research; sex bias; research animals; female animals ... See more keywords
Sex Bias in Gut Microbiome Transmission in Newly Paired Marmosets (Callithrix jacchus)
Sign Up to like & getrecommendations! Published in 2020 at "mSystems"
DOI: 10.1128/msystems.00910-19
Abstract: In this controlled study, we collected longitudinal fecal samples from 16 male and female marmoset monkeys for 2 weeks prior to and for 8 weeks after pairing in male-female dyads. We report for the first… read more here.
Keywords: gut microbiome; pairing; transmission; sex ... See more keywords
Abstract 16: The role of innate and adaptive immunity in the sex bias of LKB1-mutant lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-16
Abstract: The tumor suppressor gene, LKB1/STK11, is one of the most frequently mutated genes in lung adenocarcinoma (LUAD). A multidimensional analysis of TCGA-LUAD patient data indicates that LKB1 mutation is one of the top sex-biased mutations,… read more here.
Keywords: lkb1 mutant; sex; sex bias; lung adenocarcinoma ... See more keywords
Investigating Sex Bias in the AQ-10: A Replication Study
Sign Up to like & getrecommendations! Published in 2017 at "Assessment"
DOI: 10.1177/1073191117733548
Abstract: There are concerns that females with autism spectrum disorders (ASD) may be underidentified because of factors such as better camouflaging and poorer recognition of the signs of ASD in females. One stage at which females… read more here.
Keywords: replication study; sex bias; bias replication; study ... See more keywords
Integration of microarray data and literature mining identifies a sex bias in DPP4+CD4+ T cells in HIV-1 infection
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0239399
Abstract: HIV-1 infection exhibits a significant sex bias. This study aimed at identifying and examining lymphocyte associated sex differences in HIV-1 pathogenesis using a data-driven approach. To select targets for investigating sex differences in lymphocytes, data… read more here.
Keywords: hiv infection; literature mining; sex bias; sex differences ... See more keywords
Problems and Progress regarding Sex Bias and Omission in Neuroscience Research
Sign Up to like & getrecommendations! Published in 2017 at "eNeuro"
DOI: 10.1523/eneuro.0278-17.2017
Abstract: Visual Abstract Neuroscience research has historically ignored female animals. This neglect comes in two general forms. The first is sex bias, defined as favoring one sex over another; in this case, male over female. The… read more here.
Keywords: neuroscience; sex; sex bias; bias omission ... See more keywords
Sex Bias in Asthma Prevalence and Pathogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02997
Abstract: Sex-related differences in asthma prevalence are well established and change through the reproductive phases of life. As children, boys have increased prevalence of asthma compared to girls. However, as adults, women have increased prevalence of… read more here.
Keywords: bias asthma; sex bias; asthma prevalence; prevalence ... See more keywords