Systematic analysis of the causes of NIPS sex chromosome aneuploidy false‐positive results
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1963
Abstract: To investigate the underlying causes of false positives in NIPT of fetal sex chromosomal aneuploidies using fetal cell‐free DNA from maternal plasma. read more here.
Keywords: nips sex; analysis causes; sex chromosome; systematic analysis ... See more keywords
State‐wide increase in prenatal diagnosis of klinefelter syndrome on amniocentesis and chorionic villus sampling: Impact of non‐invasive prenatal testing for sex chromosome conditions
Sign Up to like & getrecommendations! Published in 2022 at "Prenatal Diagnosis"
DOI: 10.1002/pd.6103
Abstract: To analyze population‐based trends in the prenatal diagnosis of sex chromosome aneuploidy (SCA) since the availability of non‐invasive prenatal testing (NIPT). read more here.
Keywords: prenatal testing; sex chromosome; diagnosis; non invasive ... See more keywords
Ethical issues associated with prenatal screening using NIPT for sex chromosome aneuploidy.
Sign Up to like & getrecommendations! Published in 2022 at "Prenatal diagnosis"
DOI: 10.1002/pd.6217
Abstract: Prenatal screening for sex chromosome aneuploidies (SCAs) is increasingly available through expanded non-invasive prenatal testing (NIPT). NIPT screening for SCAs raises complex ethical issues for clinical providers, prospective parents and future children. This paper discusses… read more here.
Keywords: sex chromosome; screening scas; prenatal screening; ethical issues ... See more keywords
When a sex chromosome aneuploidy is diagnosed—views from a parent support organisation
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DOI: 10.1002/pd.6222
Abstract: Prenatal diagnosis of sex chromosome aneuploidies (SCAs) has been increasing recent years, in connection with increased availability of cell-free DNA screening (NIPT). We discuss what parents are likely to find helpful when a SCA is… read more here.
Keywords: sex chromosome; diagnosis; support; chromosome aneuploidy ... See more keywords
Prenatal diagnosis of sex chromosome aneuploidy—What do we tell the prospective parents?
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DOI: 10.1002/pd.6256
Abstract: Sex chromosome aneuploidy (SCA) can be detected on prenatal diagnostic testing and cell free DNA screening (cfDNA). High risk cfDNA results should be confirmed with diagnostic testing. This summary article serves as an update for… read more here.
Keywords: sex chromosome; prenatal diagnosis; chromosome aneuploidy;
A systematic review and meta‐analysis of cell‐free DNA testing for detection of fetal sex chromosome aneuploidy
Sign Up to like & getrecommendations! Published in 2023 at "Prenatal Diagnosis"
DOI: 10.1002/pd.6298
Abstract: The aim was to determine the accuracy of cell‐free DNA testing (cfDNA) for detecting sex chromosome aneuploidies (SCA) in singleton pregnancies. read more here.
Keywords: sex chromosome; cell free; free dna; dna testing ... See more keywords
Noninvasive prenatal detection of fetal sex chromosome abnormalities using the semiconductor sequencing platform (SSP) in Southern China
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-020-02056-2
Abstract: Noninvasive prenatal testing (NIPT) has been widely used to screen for fetal aneuploidies, including fetal sex chromosome aneuploidies (SCAs). However, there is less information on the performance of NIPT in detecting SCAs. A cohort of… read more here.
Keywords: sex chromosome; high risk; fetal sex; noninvasive prenatal ... See more keywords
Comparison of DNA fragmentation levels in spermatozoa with different sex chromosome complements.
Sign Up to like & getrecommendations! Published in 2019 at "Reproductive biomedicine online"
DOI: 10.1016/j.rbmo.2018.10.005
Abstract: RESEARCH QUESTION Do spermatozoa with different sex chromosome complements (X and Y; aneuploidy and monosomy) exhibit different degrees of DNA damage? DESIGN A prospective, observational study to measure the DNA fragmentation level and sex chromosome… read more here.
Keywords: spermatozoa different; sex chromosome; chromosome; dna fragmentation ... See more keywords
Rapid neo-sex chromosome evolution and incipient speciation in a major forest pest
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DOI: 10.1038/s41467-017-01761-4
Abstract: Genome evolution is predicted to be rapid following the establishment of new (neo) sex chromosomes, but it is not known if neo-sex chromosome evolution plays an important role in speciation. Here we combine extensive crossing… read more here.
Keywords: sex chromosome; neo sex; evolution; sex ... See more keywords
Dynamic sex chromosome expression in Drosophila male germ cells
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DOI: 10.1038/s41467-021-20897-y
Abstract: Given their copy number differences and unique modes of inheritance, the evolved gene content and expression of sex chromosomes is unusual. In many organisms the X and Y chromosomes are inactivated in spermatocytes, possibly as… read more here.
Keywords: sex chromosome; dynamic sex; expression; chromosome expression ... See more keywords
Identification of two independent X-autosome translocations in closely related mammalian (Proechimys) species
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DOI: 10.1038/s41598-019-40593-8
Abstract: Multiple sex chromosome systems have been described for several mammalian orders, with different species from the same genus sharing the same system (e.g., X1X2Y or XY1Y2). This is important because the translocated autosome may be… read more here.
Keywords: proechimys species; sex chromosome; chromosome; goeldii ... See more keywords