Aqueous solution interactions with sex hormone-binding globulin and estradiol: a theoretical investigation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biological Physics"
DOI: 10.1007/s10867-018-9505-8
Abstract: Sex hormone-binding globulin (SHBG) is a binding protein that regulates the availability of steroid hormones in the plasma. Although best known as a steroid carrier, recent studies have associated SHBG in modulating behavioral aspects related… read more here.
Keywords: hormone; energy; shbg; sex hormone ... See more keywords
Bisphenol A disrupts steroidogenesis and induces a sex hormone imbalance through c-Jun phosphorylation in Leydig cells.
Sign Up to like & getrecommendations! Published in 2017 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2017.07.004
Abstract: Bisphenol A (BPA) is a well-known endocrine disrupting chemical (EDC) that is used to manufacture plastic consumer products. It is well known that exposure to BPA can induce defects in gonad development and negatively influences… read more here.
Keywords: hormone; leydig cells; jun phosphorylation; sex hormone ... See more keywords
Estradiol induces allosteric coupling and partitioning of sex-hormone-binding globulin monomers among conformational states
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102414
Abstract: Summary Sex-hormone-binding globulin (SHBG) regulates the transport and bioavailability of estradiol. The dynamics of estradiol's binding to SHBG are incompletely understood, although it is believed that estradiol binds to each monomer of SHBG dimer with… read more here.
Keywords: hormone; shbg; estradiol binding; sex hormone ... See more keywords
Genomics of sex hormone receptor signaling in hepatic sexual dimorphism
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2017.05.025
Abstract: The liver plays a crucial role in a variety of physiological processes. Sexual dimorphism is markedly defined in liver disorders, such as fatty liver diseases and liver cancer, but barely addressed in the normal liver.… read more here.
Keywords: sexual dimorphism; dimorphism; liver; sex hormone ... See more keywords
An ultrasensitive electrochemical immunosensor for detection of sex hormone binding globulin
Sign Up to like & getrecommendations! Published in 2019 at "Microchemical Journal"
DOI: 10.1016/j.microc.2019.104010
Abstract: Abstract A novel electrochemical immunosensor was fabricated for detection of polycystic ovary syndrome (PCOS) by immobilizing horseradish peroxidase (HRP) labeled sex hormone binding globulin (SHBG) antibody (Ab) onto chitosan (CHIT), copper nanoparticles (CuNPs), iron nanoparticles… read more here.
Keywords: immunosensor; electrochemical immunosensor; electrode; sex hormone ... See more keywords
Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels In Vivo.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b01382
Abstract: The human luteinizing hormone receptor (hLH-R) is a member of the glycoprotein hormone family of GPCRs, activated by luteinizing hormone (hLH) and essentially involved in the regulation of sex hormone production. Thus, hLH-R represents a… read more here.
Keywords: hormone; bay 298; luteinizing hormone; bay ... See more keywords
Cross-sex hormone treatment and own-body perception: behavioral and brain connectivity profiles
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-80687-2
Abstract: Referrals for gender dysphoria (GD), characterized by a distressful incongruence between gender identity and at-birth assigned sex, are steadily increasing. The underlying neurobiology, and the mechanisms of the often-beneficial cross-sex hormone treatment are unknown. Here,… read more here.
Keywords: cross sex; sex; sex hormone; hormone treatment ... See more keywords
Serum sex hormone-binding globulin is associated with symptomatic late-onset hypogonadism in aging rural males: a community-based study.
Sign Up to like & getrecommendations! Published in 2021 at "Sexual health"
DOI: 10.1071/sh20201
Abstract: BACKGROUND To investigate whether serum levels of sex hormone-binding globulin (SHBG) and testosterone are associated with symptomatic late-onset hypogonadism (SLOH) in middle-aged and elderly rural Chinese males. METHODS A population-based cross-sectional study was conducted in… read more here.
Keywords: late onset; binding globulin; sex hormone; symptomatic late ... See more keywords
First trimester sex hormone-binding globulin predicts gestational diabetes mellitus in a population of Nigerian women
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2022.2114321
Abstract: Abstract There has been a steady rise in the disease burden of Gestational Diabetes Mellitus (GDM) in the sub-Saharan African region over time. Diagnostic testing for GDM is currently recommended at 24 − 28 weeks of gestation,… read more here.
Keywords: gdm; hormone binding; first trimester; gestational diabetes ... See more keywords
The association between serum sex hormone-binding globulin changes during progestin-primed ovarian stimulation and embryo outcomes: a retrospective cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2022.2112940
Abstract: Abstract Objective: This study is aimed to examine the associations between embryo outcomes and serum sex hormone-binding globulin (SHBG) changes during progestin-primed ovarian stimulation (PPOS) protocols in IVF/ICSI cycles. Research methods: This study included 2790… read more here.
Keywords: hormone binding; embryo outcomes; serum sex; sex hormone ... See more keywords
Callous-unemotional traits and early life stress predict treatment effects on stress and sex hormone functioning in incarcerated male adolescents
Sign Up to like & getrecommendations! Published in 2018 at "Stress"
DOI: 10.1080/10253890.2017.1414799
Abstract: Abstract The stress response system is highly plastic, and hormone rhythms may “adaptively calibrate” in response to treatment. This investigation assessed whether stress and sex hormone diurnal rhythms changed over the course of behavioral treatment,… read more here.
Keywords: stress sex; hormone; treatment; sex hormone ... See more keywords