Novel role of SF1 in alleviating thyroid-associated ophthalmopathy through the AMPK/mTOR signaling pathway.
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DOI: 10.1016/j.gene.2018.11.097
Abstract: BACKGROUND/AIM Thyroid-associated ophthalmopathy (TAO) is a chronic autoimmune disorder characterized by an increased volume of adipose/connective tissue. This study aims to explore whether steroidogenic factor 1 (SF1) is implicated in development of TAO through the… read more here.
Keywords: thyroid associated; mtor signaling; signaling pathway; ampk ... See more keywords
Selective interactions between diverse STEs organize the ANT-C Hox cluster
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DOI: 10.1038/s41598-018-33588-4
Abstract: The three-dimensional organization of the eukaryotic genome is important for its structure and function. Recent studies indicate that hierarchies of chromatin loops underlie important aspects of both genomic organization and gene regulation. Looping between insulator… read more here.
Keywords: chromatin; hox; insulator; gene ... See more keywords