Mutations of GNAQ, GNA11, SF3B1, EIF1AX, PLCB4 and CYSLTR in Uveal Melanoma in Chinese Patients
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DOI: 10.1159/000502888
Abstract: Background: The purpose of this study is to determine the mutation frequencies of key driver genes in uveal melanoma (UM) in Chinese patients and to detect associations between metastasis and the mutation of these genes.… read more here.
Keywords: melanoma chinese; gnaq gna11; metastasis; uveal melanoma ... See more keywords
Metastatic cutaneous apocrine carcinoma: a multidisciplinary approach incorporating endocrine therapy
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Dermatology"
DOI: 10.1684/ejd.2018.3282
Abstract: and check for possible sequencing errors. We detected 29 somatic mutations, including a recurrent somatic R625C mutation in SF3B1 (frequency, 43.9%). Hotspot neomorphic SF3B1 mutations have been identified in uveal melanoma and subsequently in mucosal… read more here.
Keywords: sf3b1; mucosal melanoma; sf3b1 eif1ax; therapy ... See more keywords