Articles with "sf3b4" as a keyword



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Enabled homolog (ENAH) regulated by RNA binding protein splicing factor 3b subunit 4 (SF3B4) exacerbates the proliferation, invasion and migration of hepatocellular carcinoma cells via Notch signaling pathway

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2021.2023983

Abstract: ABSTRACT Enabled homolog (ENAH) is an actin-binding protein that implicated in multiple malignant tumors. High ENAH expression has been verified to be associated with poor prognosis in hepatocellular carcinoma (HCC). We aimed to reveal the… read more here.

Keywords: invasion migration; notch signaling; hcc; enah ... See more keywords
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SF3B4 Depletion Retards the Growth of A549 Non-Small Cell Lung Cancer Cells via UBE4B-Mediated Regulation of p53/p21 and p27 Expression

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Published in 2022 at "Molecules and Cells"

DOI: 10.14348/molcells.2022.0037

Abstract: Splicing factor B subunit 4 (SF3B4), a component of the U2-pre-mRNA spliceosomal complex, contributes to tumorigenesis in several types of tumors. However, the oncogenic potential of SF3B4 in lung cancer has not yet been determined.… read more here.

Keywords: p21; cell; depletion; expression ... See more keywords
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GPAA1 promotes the proliferation, invasion and migration of hepatocellular carcinoma cells by binding to RNA-binding protein SF3B4

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Published in 2022 at "Oncology Letters"

DOI: 10.3892/ol.2022.13280

Abstract: It has previously been reported that glycosylphosphatidylinositol anchor attachment 1 (GPAA1) is overexpressed in hepatocellular carcinoma (HCC); however, its role in regulating the development of HCC remains unknown. The present study aimed to examine the… read more here.

Keywords: hepatocellular carcinoma; hcc; gpaa1; migration ... See more keywords