Synthesis of Pyridine-SF4-Isoxazolines Using the Functionality of trans-Tetrafluoro-λ6-sulfanyl Rodlike Linkers.
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DOI: 10.1021/acs.orglett.2c01046
Abstract: The tetrafluoro-λ6-sulfanyl (SF4) moiety has been relatively undeveloped since its discovery in the 1970s. In this study, we synthesized pyridine-SF4-isoxazolines, in which the two heterocycles are connected by a rodlike trans-SF4 linker, via the regioselective… read more here.
Keywords: sf4; tetrafluoro sulfanyl; synthesis pyridine; isoxazolines using ... See more keywords
TBHP Promotes Cross-Dehydrogenative Coupling of SF4 Alkynes with Tetrahydroisoquinolines under Copper Catalysis.
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DOI: 10.1021/acs.orglett.4c02599
Abstract: We present a viable approach for the cross-dehydrogenative coupling of Het-SF4-alkynes with tetrahydroisoquinolines under oxidative conditions, using TBHP and copper catalysts. These newly developed conditions boast enhanced yields and a more extensive range of substrates,… read more here.
Keywords: sf4; sf4 alkynes; alkynes tetrahydroisoquinolines; cross dehydrogenative ... See more keywords