The isothiocyanate sulforaphane prevents mitochondrial impairment and neuroinflammation in the human dopaminergic SH-SY5Y and in the mouse microglial BV2 cells: role for heme oxygenase-1.
Sign Up to like & getrecommendations! Published in 2022 at "Metabolic brain disease"
DOI: 10.1007/s11011-022-00990-x
Abstract: Sulforaphane (SFN) promotes protective effects in different cell types. Nonetheless, it remains to be clarified by which mechanism SFN exerts benefits in mammalian cells. Mitochondria are a major source of adenosine triphosphate (ATP) and reactive… read more here.
Keywords: sfn; bv2 cells; mitochondrial impairment; heme oxygenase ... See more keywords
Current Diagnosis and Treatment of Painful Small Fiber Neuropathy
Sign Up to like & getrecommendations! Published in 2019 at "Current Neurology and Neuroscience Reports"
DOI: 10.1007/s11910-019-1020-1
Abstract: Purpose of ReviewSmall fiber neuropathy (SFN) could cause significant morbidity due to neuropathic pain and autonomic dysfunction. SFN is underdiagnosed and the knowledge on the condition is limited among general public and health care professionals.… read more here.
Keywords: fiber neuropathy; etiology; treatment; current diagnosis ... See more keywords
NMR study on the stabilization and chiral discrimination of sulforaphane enantiomers and analogues by cyclodextrins.
Sign Up to like & getrecommendations! Published in 2018 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2017.12.022
Abstract: Sulforaphane (SFN), a phytochemical isolated from broccoli, is an important antitumoral compound with additional beneficial effect on other important diseases. However, the chemical instability of SFN has hampered its clinical use. In order to circumvent… read more here.
Keywords: stabilization; sfn; study; inclusion complexes ... See more keywords
DNA methylation patterns of the S100A14, POU2F3 and SFN genes in equine sarcoid tissues.
Sign Up to like & getrecommendations! Published in 2018 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2018.07.006
Abstract: Genetic and epigenetic alterations in the equine sarcoid, a locally invasive skin tumour of equids, are still poorly characterized. Numerous studies have provided reliable evidence for the relationship between the development of cancer and the… read more here.
Keywords: methylation; s100a14 pou2f3; equine sarcoid; methylation patterns ... See more keywords
The chemopreventive isothiocyanate sulforaphane reduces anoikis resistance and anchorage‐independent growth in non‐small cell human lung cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.10.020
Abstract: ABSTRACT The capacity of cancer cells to resist detachment‐induced apoptosis, i.e. anoikis, as well as anchorage‐independent growth are crucial prerequisites for tumor metastasis. Therefore, agents interfering these properties may provide novel anti‐metastatic strategies. Sulforaphane (SFN),… read more here.
Keywords: anchorage independent; sfn; independent growth; cancer cells ... See more keywords
UVB Drives Metabolic Rewiring and Epigenetic Reprograming and Protection by Sulforaphane in Human Skin Keratinocytes.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.1c00432
Abstract: Sulforaphane (SFN) is a potent anticancer agent which could protect the skin from ultraviolet (UV) radiation-induced insults. Currently, the metabolic rewiring and epigenetic reprograming induced by UVB and the role of SFN in UVB-mediated skin… read more here.
Keywords: uvb drives; sfn; epigenetic reprograming; metabolic rewiring ... See more keywords
Sulforaphane Suppresses MCF-7 Breast Cancer Cells Growth via miR-19/PTEN Axis to Antagonize the Effect of Butyl Benzyl Phthalate
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2022.2156555
Abstract: Abstract Sulforaphane (SFN), a major isothiocyanate found in cruciferous vegetables, reportedly exerts extensive antitumor effects. Butyl benzyl phthalate (BBP), a widely used plasticizer, plays a crucial role in the promotion of breast cancer. In the… read more here.
Keywords: sfn; growth; breast cancer; mir ... See more keywords
Sulforaphane Effects on Cardiac Function and Calcium-Handling–Related Proteins in 2 Experimental Models of Heart Disease: Ischemia-Reperfusion and Infarction
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001191
Abstract: Abstract: Sulforaphane (SFN) is a natural exogenous antioxidant from cruciferous vegetables already shown to improve cardiac function in cardiovascular diseases. The aim of this study was to analyze the effect of SFN treatment on the… read more here.
Keywords: cardiac function; ischemia; calcium handling; sfn ... See more keywords
Small fiber neuropathies: expanding their etiologies
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000001103
Abstract: Purpose of review Several conditions have been associated with the development of small fiber neuropathy (SFN). The list of metabolic, immune-mediated, infectious, toxic, drugs-related, and hereditary conditions is still growing and various hypotheses are made… read more here.
Keywords: sfn; neuropathies expanding; expanding etiologies; small fiber ... See more keywords
Using LDM to Achieve Seamless Local Service Insertion and Local Program Coverage in SFN Environment
Sign Up to like & getrecommendations! Published in 2017 at "IEEE Transactions on Broadcasting"
DOI: 10.1109/tbc.2016.2630302
Abstract: Layered division multiplexing (LDM) is a spectrum efficient non-orthogonal multiplexing technology that has been adopted in the Advanced Television Systems Committee (ATSC) 3.0 Physical Layer Standard as a baseline technology. This paper studies a two-layer… read more here.
Keywords: lower layer; layer; local service; coverage ... See more keywords
From MFN to SFN: Performance Prediction Through Machine Learning
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Broadcasting"
DOI: 10.1109/tbc.2021.3132804
Abstract: In the last decade, the transition of digital terrestrial television (DTT) systems from multi-frequency networks (MFNs) to single-frequency networks (SFNs) has become a reality. SFN offers multiple advantages concerning MFN, such as more efficient management… read more here.
Keywords: sfn gain; sfn; machine learning; performance ... See more keywords