SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia
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DOI: 10.1182/bloodadvances.2021006076
Abstract: Key Points SFPQ-ABL1 is localized to the nuclear compartment and is a relatively weaker driver of cellular proliferation compared with BCR-ABL1. SFPQ-ABL1 and BCR-ABL1 activate distinct signaling networks, both of which converge on inhibiting apoptosis… read more here.
Keywords: signaling networks; abl1 bcr; bcr abl1; sfpq abl1 ... See more keywords