Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons
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DOI: 10.1098/rsob.220187
Abstract: Splicing factor proline- and glutamine-rich (SFPQ) is a nuclear RNA-binding protein that is involved in a wide range of physiological processes including neuronal development and homeostasis. However, the mislocalization and cytoplasmic aggregation of SFPQ are… read more here.
Keywords: familial als; associated sfpq; sfpq cytoplasmic; sfpq ... See more keywords