Methylation-associated silencing of SFRP1 gene in high-grade serous ovarian carcinomas.
Sign Up to like & getrecommendations! Published in 2017 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2017.07.002
Abstract: Wnt is a highly conserved signaling pathway responsible for tissue regeneration, maintenance and differentiation of stem cells in adults. Its aberrant activation through reduced expression of Wnt signaling pathway inhibitors, such as proteins from the… read more here.
Keywords: protein expression; grade serous; sfrp1 protein; expression ... See more keywords
SFRP1 increases TMPRSS2-ERG expression promoting neoplastic features in prostate cancer in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Cell International"
DOI: 10.1186/s12935-020-01333-5
Abstract: Background Prostate cancer (PCa) is the second cause of cancer related death in North American men. Androgens play an important role in its progression by regulating the expression of several genes including fusion ones that results from… read more here.
Keywords: tmprss2 erg; sfrp1 protein; expression; cancer ... See more keywords