Interference of miR-943-3p with secreted frizzled-related proteins4 (SFRP4) in an asthma mouse model
Sign Up to like & getrecommendations! Published in 2019 at "Cell and Tissue Research"
DOI: 10.1007/s00441-019-03026-6
Abstract: The aim of this study is to investigate the potential roles of miR-943-3p and its target gene secreted frizzled-related proteins4 (SFRP4) in allergic asthma and elucidate its underlying mechanism, which may prompt a new clue… read more here.
Keywords: frizzled related; mir 943; sfrp4; asthma ... See more keywords
Secreted frizzled-related protein 4 exerts anti-atherosclerotic effects by reducing inflammation and oxidative stress.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2022.174901
Abstract: Atherosclerosis and its sequelae, such as coronary artery disease (CAD), are the most common diseases worldwide and the leading causes of morbidity and mortality in most countries. Our previous studies have shown that circulating secreted… read more here.
Keywords: related protein; sfrp4; reducing inflammation; frizzled related ... See more keywords
Demethylation of the SFRP4 Promoter Drives Gastric Cancer Progression via the Wnt Pathway
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DOI: 10.1158/1541-7786.mcr-20-0933
Abstract: Wnt signaling is believed to be an important contributor to tumor development and has been reported to be modulated by secreted frizzled-related proteins (SFRP). Nevertheless, the role of secreted frizzled-related protein 4 (SFRP4) in tumorigenesis… read more here.
Keywords: expression; sfrp4; progression; cancer ... See more keywords
Human epicardial adipose tissue-derived and circulating secreted frizzled-related protein 4 (SFRP4) levels are increased in patients with coronary artery disease
Sign Up to like & getrecommendations! Published in 2017 at "Cardiovascular Diabetology"
DOI: 10.1186/s12933-017-0612-9
Abstract: BackgroundPrevious studies have demonstrated that secreted frizzled-related protein 4 (SFRP4) is associated with impaired glucose and triglyceride metabolism in patients with stable coronary artery disease. In the present study, we investigated human epicardial adipose tissue… read more here.
Keywords: protein; cad; expression; sfrp4 ... See more keywords
SFRP4 protein expression is reduced in high grade astrocytomas which is not caused by the methylation of its promoter
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2024.1398872
Abstract: Introduction Epigenetics play a vital role in stratifying CNS tumors and gliomas. The importance of studying Secreted frizzled-related protein 4 (SFRP4) in gliomas is to improve diffuse glioma methylation profiling. Here we examined the methylation… read more here.
Keywords: methylation; promoter; sfrp4; expression ... See more keywords
PKA-Mediated Phosphorylation of SFRP4 Promotes Wnt/β-Catenin Activation and Cancer Stemness in Gastric Cancer
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms26125572
Abstract: Secreted Frizzled-related protein 4 (SFRP4) has been identified as a patient-level biomarker of the stem-like subtype of gastric cancer (GC), which is associated with poor prognosis and resistance to chemotherapy. Although multiple studies have documented… read more here.
Keywords: cancer; phosphorylation sfrp4; pka; gastric cancer ... See more keywords
Proteomic detection of COX-2 pathway-related factors in patients with adenomyosis
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DOI: 10.7717/peerj.16784
Abstract: Background Investigating the relationship between cyclooxygenase-2 (COX-2) pathway-related factors and clinical features in patients with adenomyosis by proteomics could provide potential therapeutic targets. Methods This study recruited 40 patients undergoing surgical hysterectomy and pathological diagnosis… read more here.
Keywords: pathway related; related factors; cox pathway; sfrp4 ... See more keywords