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   Articles with "sgc7901" as a keyword



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DJ-1 overexpression confers the multidrug resistance phenotype to SGC7901 cells by upregulating P-gp and Bcl-2.

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recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.08.131

Abstract: Gastric cancer (GC) is one of the most malignant tumors with high incidence and mortality worldwide, and the multidrug resistance (MDR) often results in chemotherapy failure in GC. DJ-1 has been well indicated to be… read more here.

Keywords: sgc7901 cells; gastric cancer; upregulating bcl; sgc7901 ... See more keywords
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Gastrin induces multidrug resistance via the degradation of p27Kip1 in the gastric carcinoma cell line SGC7901.

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recommendations! Published in 2017 at "International journal of oncology"

DOI: 10.3892/ijo.2017.3983

Abstract: Multidrug resistance (MDR) is one of the major reasons for the failure of chemotherapy-based gastric carcinoma (GC) treatments, hence, biologically based therapies are urgently needed. Gastrin (GAS), a key gastrointestinal (GI) hormone, was found to be… read more here.

Keywords: vcr sgc7901; gas; sgc7901 vcr; pcdna3 gas ... See more keywords
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Quantitative proteomics analysis of the role of tetraspanin-8 in the drug resistance of gastric cancer.

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recommendations! Published in 2018 at "International journal of oncology"

DOI: 10.3892/ijo.2017.4231

Abstract: Gastric cancer, due to its high incidence rate, is the second leading cause of cancer-related mortality worldwide. Chemotherapy is an important component of the multimodal treatment for gastric cancer; however, a significant impediment to successful… read more here.

Keywords: gastric cancer; sgc7901; tspan8; resistance ... See more keywords
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miR‑138‑5p modulates the expression of excision repair cross‑complementing proteins ERCC1 and ERCC4, and regulates the sensitivity of gastric cancer cells to cisplatin.

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recommendations! Published in 2019 at "Oncology reports"

DOI: 10.3892/or.2018.6907

Abstract: The microRNA (miR)‑138‑5p affects the chemotherapeutic sensitivity of several human cancer types. In the present study, the expression and regulatory mechanisms of miR‑138‑5p were investigated in the gastric cancer cell line SGC7901 and its cisplatin‑resistant… read more here.

Keywords: gastric cancer; mir 138; sgc7901; ercc1 ercc4 ... See more keywords