Cell-autonomous epithelial activation of AIM2 (absent in melanoma-2) inflammasome by cytoplasmic DNA accumulations in primary Sjögren's syndrome.
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DOI: 10.1016/j.jaut.2019.102381
Abstract: Primary Sjögren's syndrome (SS) is characterized by chronic periductal inflammatory infiltrates in the salivary glands. Several previous studies have indicated that the ductal epithelia of SS patients play a pro-inflammatory role and manifest an intrinsically… read more here.
Keywords: sgec lines; aim2; dna; cytoplasmic dna ... See more keywords