Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader
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DOI: 10.1021/acschembio.9b00505
Abstract: SGK3 is a PX domain containing protein kinase activated at endosomes downstream of class 1 and 3 PI3K family members by growth factors and oncogenic mutations. SGK3 plays a key role in mediating resistance of… read more here.
Keywords: sgk3 protac1; sgk3; inhibitor; protac ... See more keywords