Improved Erythrocyte Deformability Induced by Sodium-Glucose Cotransporter 2 Inhibitors in Type 2 Diabetic Patients
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-020-07067-w
Abstract: Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are antidiabetic drugs that improve cardiovascular outcomes. Hemoglobin and hematocrit values increase after SGLT-2 inhibitor administration. Although these factors increase blood viscosity and the risk of cardiovascular disease, SGLT-2 inhibitors… read more here.
Keywords: sglt inhibitor; inhibitor; erythrocyte deformability; deformability ... See more keywords
Remogliflozin: the new low cost SGLT-2 inhibitor for type 2 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2020 at "Diabetology International"
DOI: 10.1007/s13340-020-00472-4
Abstract: SGLT-2 inhibitors have recently emerged as an important class of oral drugs for treatment of type 2 diabetes mellitus, especially in patients with cardiovascular or renal impairment, recommended in all recent treatment guidelines. They have… read more here.
Keywords: sglt inhibitor; sglt; type diabetes; diabetes mellitus ... See more keywords
“WHICH ONE SHOULD I CHOOSE, A GLP-1RA OR A SGLT2 INHIBITOR? OR MAYBE BOTH?’’. A POOLED ANALYSIS OF CARDIOVASCULAR OUTCOME TRIALS
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000837324.54362.4b
Abstract: Objective: Glucagon-like peptide 1 receptor agonists (GLP-1RAs) and sodium–glucose cotransporter 2 (SGLT2) inhibitors are prioritized for the treatment of patients with type 2 diabetes mellitus (T2DM) to reduce major adverse cardiovascular events (MACE), hospitalization for… read more here.
Keywords: outcome; inhibitor glp; sglt inhibitor; glp 1ra ... See more keywords
Very low carbohydrate diet and SGLT-2-inhibitor: double jeopardy in relation to ketoacidosis
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Case Reports"
DOI: 10.1136/bcr-2018-227516
Abstract: Diabetic euglycaemic ketoacidosis is a possible adverse effect of sodium–glucose co-transporter-2 inhibitors (SGLT2i). We report a case in which the combination of SGLT2i and a strict very low-carbohydrate diet led to severe diabetic ketoacidosis in… read more here.
Keywords: inhibitor double; sglt inhibitor; ketoacidosis; carbohydrate diet ... See more keywords
SGLT-2 inhibitor associated euglycaemic diabetic ketoacidosis in an orthopaedic trauma patient
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2022-250233
Abstract: Euglycaemic diabetic ketoacidosis is a serious but rare adverse effect of treatment with sodium-glucose cotransporter-2 (SGLT-2) inhibitors. A man in his 60s with type 2 diabetes mellitus underwent total hip replacement for an intracapsular neck… read more here.
Keywords: sglt inhibitor; diabetic ketoacidosis; euglycaemic diabetic;
Abstract 13169: US Prevalence Estimates of Individuals With Diabetes and Chronic Kidney Disease Indicated for SGLT-2 Inhibitor Initiation
Sign Up to like & getrecommendations! Published in 2020 at "Circulation"
DOI: 10.1161/circ.142.suppl_3.13169
Abstract: Introduction: Since the CREDENCE trial results, the American Diabetes Association (ADA) recommends SGLT-2 inhibitors as first line therapy for patients with stage III Chronic Kidney Disease (CKD) or proteinuric CKD, regardless of baseline A1C. We… read more here.
Keywords: chronic kidney; sglt inhibitor; disease; kidney disease ... See more keywords
Effects of an SGLT Inhibitor on the Production, Toxicity, and Elimination of Gut-Derived Uremic Toxins: A Call for Additional Evidence
Sign Up to like & getrecommendations! Published in 2022 at "Toxins"
DOI: 10.3390/toxins14030210
Abstract: Sodium–glucose cotransporter (SGLT) inhibitors are a class of oral hypoglycemic agents, which, in recent years, have been shown to improve renal and cardiovascular outcomes in patients with diabetic and non-diabetic chronic kidney disease. There remains… read more here.
Keywords: gut; inhibitor production; sglt inhibitor; effects sglt ... See more keywords
Anti-Inflammatory Effect for Atherosclerosis Progression by Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitor in a Normoglycemic Rabbit Model
Sign Up to like & getrecommendations! Published in 2020 at "Korean Circulation Journal"
DOI: 10.4070/kcj.2019.0296
Abstract: Background and Objectives We sought to investigate an anti-atherosclerotic and anti-inflammatory effect of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in normoglycemic atherosclerotic rabbit model. Methods Male New Zealand white rabbits (n=26) were fed with a 1% high-cholesterol… read more here.
Keywords: anti inflammatory; sglt inhibitor; inhibitor; inflammatory effect ... See more keywords