Expression of SGLT1 in the Mouse Endometrial Epithelium and its Role in Early Embryonic Development and Implantation
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive Sciences"
DOI: 10.1007/s43032-021-00480-y
Abstract: Many functional activities of endometrium epithelium are energy consuming which are very important for maintaining intrauterine environment needed by early embryonic development and establishment of implantation window. Glucose is a main energy supplier and one… read more here.
Keywords: endometrial epithelium; expression sglt1; epithelium; implantation ... See more keywords
SGL5213, a novel and potent intestinal SGLT1 inhibitor, suppresses intestinal glucose absorption and enhances plasma GLP‐1 and GLP‐2 secretion in rats
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2019.03.023
Abstract: ABSTRACT Sodium‐glucose cotransporter 1 (SGLT1) is the primary transporter for glucose absorption from digested nutrients in the gastrointestinal tract. Intestinal SGLT1 inhibition reduces post‐prandial hyperglycemia and enhances the increase of plasma glucagon‐like peptide‐1 (GLP‐1) levels.… read more here.
Keywords: sglt1 inhibitor; glp; glucose absorption; intestinal sglt1 ... See more keywords
Rice (Oryza sativa japonica) albumin hydrolysates suppress postprandial blood glucose elevation by adsorbing glucose and inhibiting Na+-d-glucose cotransporter SGLT1 expression
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2019.103603
Abstract: Abstract The mechanism of the suppressive effect of rice albumin (RA) on postprandial hyperglycemia after glucose loading was investigated. In order to examine if small peptides derived from RA are responsible for prevention of postprandial… read more here.
Keywords: rice; expression; blood glucose; sglt1 ... See more keywords
SGLT1 participates in the development of vascular cognitive impairment in a mouse model of small vessel disease
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2020.134929
Abstract: Sodium/glucose cotransporter 1 (SGLT1) participates in ischemia-reperfusion-induced cerebral injury. However, whether SGLT1 participates in the development of small vessel disease induced-vascular cognitive impairment is unknown. We examined the roles of SGLT1 in the development of… read more here.
Keywords: small vessel; sglt1; development; mouse ... See more keywords
Characterization of myocardial sodium-glucose cotransporter 1 expression in humans with heart failure and reduced ejection fraction
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.0938
Abstract: In diabetic patients, multiple cardiovascular outcome trials consistently showed the robust cardioprotective effects of the novel antidiabetic agents, sodium glucose cotransporter 2 (SGLT2) inhibitors. However, the DAPA-HF study using the SGLT2 inhibitor dapagliflozin have extended… read more here.
Keywords: heart; expression; ihd t2dm; sglt1 ... See more keywords
Investigating sodium-glucose co-transporters 1 (SGLT1) in myocardium and its role in hyperglycaemia ischaemia-reperfusion injury
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.1577
Abstract: Hyperglycaemia is a common finding in diabetic and non-diabetic patients presenting with ACS, and is a powerful predictor of prognosis and mortality. The role of hyperglycaemia in ischemia-reperfusion injury (IRI) is not fully understood, and… read more here.
Keywords: myocardium; reperfusion; hyperglycaemia; role ... See more keywords
P6278Ageing is associated with increased endothelial sodium-glucose cotransporter 1 expression at arterial sites at risk promoting enhanced anthocyanin accumulation and improved vascular oxidative stress
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz746.0877
Abstract: Ageing is characterized by endothelial dysfunction and vascular oxidative stress affecting initially arterial sites at risk. Anthocyanin-rich products are potent stimulators of the endothelial formation of nitric oxide. Sodium-glucose co-transporter 1 (SGLT1) expression has been… read more here.
Keywords: accumulation; aorta; aortic arch; stress ... See more keywords
20 Investigating sodium-glucose co-transporter 1 (SGLT1) in myocardium and its role in hyperglycemia ischaemia-reperfusion injury
Sign Up to like & getrecommendations! Published in 2020 at "Heart"
DOI: 10.1136/heartjnl-2020-bcs.20
Abstract: Introduction Hyperglycaemia is a common finding in diabetic and non-diabetic patients presenting with ACS, and is a powerful predictor of prognosis and mortality. The role of hyperglycaemia in ischemia-reperfusion injury (IRI) is not fully understood,… read more here.
Keywords: role; reperfusion injury; reperfusion; myocardium ... See more keywords
Sodium-Dependent Glucose Transporter 1 (SGLT1) Stabled by HER2 Promotes Breast Cancer Cell Proliferation by Activation of the PI3K/Akt/mTOR Signaling Pathway in HER2+ Breast Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Disease Markers"
DOI: 10.1155/2020/6103542
Abstract: Aerobic glycolysis is a hallmark of tumor cells. SGLT1 plays a vital role in glucose metabolism. However, whether SGLT1 could promote cell growth and proliferation in breast cancer remains unclear. Here, we investigated the expression… read more here.
Keywords: her2 breast; breast cancer; cancer; sglt1 ... See more keywords
SGLT1 Deficiency Turns Listeria Infection into a Lethal Disease in Mice
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000479197
Abstract: Background: Cellular glucose uptake may involve either non-concentrative glucose carriers of the GLUT family or Na+-coupled glucose-carrier SGLT1, which accumulates glucose against glucose gradients and may thus accomplish cellular glucose uptake even at dramatically decreased… read more here.
Keywords: infection; listeria infection; mice; sglt1 ... See more keywords