SGL5213, a novel and potent intestinal SGLT1 inhibitor, suppresses intestinal glucose absorption and enhances plasma GLP‐1 and GLP‐2 secretion in rats
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DOI: 10.1016/j.ejphar.2019.03.023
Abstract: ABSTRACT Sodium‐glucose cotransporter 1 (SGLT1) is the primary transporter for glucose absorption from digested nutrients in the gastrointestinal tract. Intestinal SGLT1 inhibition reduces post‐prandial hyperglycemia and enhances the increase of plasma glucagon‐like peptide‐1 (GLP‐1) levels.… read more here.
Keywords: sglt1 inhibitor; glp; glucose absorption; intestinal sglt1 ... See more keywords