Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2
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DOI: 10.1007/s00125-018-4656-5
Abstract: The concentration of glucose in plasma is held within narrow limits (4–10 mmol/l), primarily to ensure fuel supply to the brain. Kidneys play a role in glucose homeostasis in the body by ensuring that glucose is… read more here.
Keywords: glucose handling; sglt2; physiology; renal glucose ... See more keywords
Investigational Agents Targeting SGLT1 and SGLT2 in the Treatment of Type 2 Diabetes Mellitus.
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DOI: 10.2174/1389450124666230503120930
Abstract: Targeting sodium-dependent glucose transporters (SGLT1 and SGLT2) represents a new class of pharmacotherapy for type 2 diabetes mellitus, a major global health issue with an increasing social and economic burden. Following recent successes in market… read more here.
Keywords: investigational agents; type diabetes; sglt1 sglt2; diabetes mellitus ... See more keywords